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中华乳腺病杂志(电子版) ›› 2024, Vol. 18 ›› Issue (04) : 241 -243. doi: 10.3877/cma.j.issn.1674-0807.2024.04.009

综述

THP方案新辅助治疗HER-2阳性乳腺癌的研究现状
王丽君1, 辛岗1, 胡崇珠2,()   
  1. 1. 067000 承德医学院研究生院;071000 保定市第一中心医院乳腺外一科
    2. 071000 保定市第一中心医院乳腺外一科
  • 收稿日期:2023-12-28 出版日期:2024-08-01
  • 通信作者: 胡崇珠
  • 基金资助:
    保定市科技计划项目(2141ZF242)

THP regimen in neoadjuvant treatment of HER-2 positive breast cancer

Lijun Wang, Gang Xin, Chongzhu Hu()   

  • Received:2023-12-28 Published:2024-08-01
  • Corresponding author: Chongzhu Hu
引用本文:

王丽君, 辛岗, 胡崇珠. THP方案新辅助治疗HER-2阳性乳腺癌的研究现状[J]. 中华乳腺病杂志(电子版), 2024, 18(04): 241-243.

Lijun Wang, Gang Xin, Chongzhu Hu. THP regimen in neoadjuvant treatment of HER-2 positive breast cancer[J]. Chinese Journal of Breast Disease(Electronic Edition), 2024, 18(04): 241-243.

新辅助治疗是HER-2阳性乳腺癌综合治疗体系中的重要组成部分。权威指南一致推荐曲妥珠单克隆抗体加帕妥珠单克隆抗体联合紫杉类和卡铂(TCbHP)方案作为早期HER-2阳性乳腺癌新辅助治疗的首选方案。然而,关于是否将曲妥珠单克隆抗体加帕妥珠单克隆抗体联合紫杉类药物(THP)方案作为首选方案,目前尚存较大争议。本文系统性回顾了THP方案在新辅助治疗HER-2阳性乳腺癌中的研究。虽然THP方案已证明安全且有效,但与TCbHP方案的直接比较研究较少,其作为HER-2阳性乳腺癌新辅助治疗的首选方案地位仍需进一步研究,以明确THP方案的最合适人群,并为临床决策提供依据。

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