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中华乳腺病杂志(电子版) ›› 2022, Vol. 16 ›› Issue (02) : 106 -109. doi: 10.3877/cma.j.issn.1674-0807.2022.02.007

综述

乳腺癌化疗剂量强度的认识与发展
田艳1, 孙明霞1, 吴世凯1,()   
  1. 1. 100009 北京大学第一医院肿瘤化疗科
  • 收稿日期:2020-04-30 出版日期:2022-04-01
  • 通信作者: 吴世凯

Understanding of chemotherapy dose intensity in breast cancer

Yan Tian1, Mingxia Sun1, Shikai Wu1()   

  • Received:2020-04-30 Published:2022-04-01
  • Corresponding author: Shikai Wu
引用本文:

田艳, 孙明霞, 吴世凯. 乳腺癌化疗剂量强度的认识与发展[J]. 中华乳腺病杂志(电子版), 2022, 16(02): 106-109.

Yan Tian, Mingxia Sun, Shikai Wu. Understanding of chemotherapy dose intensity in breast cancer[J]. Chinese Journal of Breast Disease(Electronic Edition), 2022, 16(02): 106-109.

乳腺癌是威胁女性健康最常见的恶性肿瘤之一。在乳腺癌多种治疗方法中,化疗仍然是不可撼动的基石,而随着时间的推移,化疗的模式却在逐渐变化。对于早期乳腺癌,剂量密集型化疗可明显改善高危患者的预后;对于晚期乳腺癌,由于其不可治愈性,除需要使肿瘤迅速缩小或症状迅速缓解的患者一线选择联合化疗外,其余患者应首选单药化疗,而在疾病达到控制后,应采取有效维持治疗,从而延缓复发,改善患者生活质量并提高患者总生存率。早期乳腺癌与晚期乳腺癌化疗的剂量强度呈现出逐渐相反的趋势,化疗则更侧重于全程管理,需要平衡疗效和不良反应。笔者旨在阐述化疗剂量强度在早期与晚期乳腺癌治疗中呈现出的不同趋势。

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