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中华乳腺病杂志(电子版) ›› 2023, Vol. 17 ›› Issue (06) : 378 -380. doi: 10.3877/cma.j.issn.1674-0807.2023.06.011

病例报告

乳腺原发上皮样血管内皮瘤一例
冯雪园, 韩萌萌, 马宁()   
  1. 071000 河北省保定市第一中心医院乳腺外二科
  • 收稿日期:2022-11-08 出版日期:2023-12-01
  • 通信作者: 马宁

Primary epithelioid hemangioendothelioma of the breast: one case report

Xueyuan Feng, Mengmeng Han, Ning Ma()   

  • Received:2022-11-08 Published:2023-12-01
  • Corresponding author: Ning Ma
引用本文:

冯雪园, 韩萌萌, 马宁. 乳腺原发上皮样血管内皮瘤一例[J/OL]. 中华乳腺病杂志(电子版), 2023, 17(06): 378-380.

Xueyuan Feng, Mengmeng Han, Ning Ma. Primary epithelioid hemangioendothelioma of the breast: one case report[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2023, 17(06): 378-380.

上皮样血管内皮瘤(epithelioid hemangioendothelioma,EHE)是一种罕见的血管肉瘤,通常表现为低度恶性。EHE于1982年被首次报道[1],发病率<0.1/100 000。原发于乳腺的EHE则更为少见,国外由Insabato等[2]于1999年首次报道,国内由徐静[3]等于2013年首次报道,目前文献可查的乳腺EHE病例不足20例。本文介绍1例乳腺原发EHE,总结其临床诊断和治疗经验,供同道参考。

图1 原发上皮样血管内皮瘤患者右乳超声图
图2 原发上皮样血管内皮瘤患者术后病理结果 a图可见黏液性间质中大量上皮样肿瘤细胞(HE ×100);b图可见上皮样肿瘤细胞排列呈巢状、条索状,细胞质嗜酸性染色(HE ×200);c图可见原始血管腔形成的胞质内空泡,部分可见红细胞(HE ×200)
图3 原发上皮样血管内皮瘤患者术后免疫组织化学染色结果 a图为肿瘤细胞CD31阳性(HE ×200);b图为肿瘤细胞成红细胞特异性转化基因相关基因阳性(HE ×100)
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