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中华乳腺病杂志(电子版) ›› 2022, Vol. 16 ›› Issue (01) : 34 -38. doi: 10.3877/cma.j.issn.1674-0807.2022.01.006

综述

微RNA对乳腺癌细胞代谢的影响
付柏杨1, 陈晰1, 梁文龙1, 王瑶1, 张建国,1   
  1. 1. 150086 哈尔滨医科大学附属第二医院乳腺外科
  • 收稿日期:2021-12-01 出版日期:2022-02-01
  • 通信作者: 张建国
  • 基金资助:
    国家自然科学基金资助项目(81972469)

Effect of microRNA on metabolism of breast cancer cells

Baiyang Fu1, Xi Chen1, Wenlong Liang1   

  • Received:2021-12-01 Published:2022-02-01
引用本文:

付柏杨, 陈晰, 梁文龙, 王瑶, 张建国. 微RNA对乳腺癌细胞代谢的影响[J/OL]. 中华乳腺病杂志(电子版), 2022, 16(01): 34-38.

Baiyang Fu, Xi Chen, Wenlong Liang. Effect of microRNA on metabolism of breast cancer cells[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2022, 16(01): 34-38.

乳腺癌是全世界女性中发病率、病死率最高的恶性肿瘤。尽管关于乳腺癌生物代谢过程的研究越来越多,但是肿瘤基因对代谢重编程的影响尚不明确。微RNA(miRNA)是一类具有调控功能的小分子非编码核糖核酸,与乳腺癌的多种生物学过程相关。笔者从糖、氨基酸、蛋白质及其共同的代谢通路切入,系统描述了miRNA在乳腺癌代谢中的作用,并且总结miRNA对乳腺癌诊断、治疗、预后的临床意义和当前研究的不足。

表1 miRNA在乳腺癌中的表达情况及其调控的代谢酶
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