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中华乳腺病杂志(电子版) ›› 2020, Vol. 14 ›› Issue (02) : 124 -128. doi: 10.3877/cma.j.issn.1674-0807.2020.02.013

所属专题: 文献

综述

乳腺癌保留乳房手术后局部复发的相关因素分析
肖琪1, 窦怡1, 熊伟1, 谭金祥1,()   
  1. 1. 400016 重庆医科大学附属第一医院内分泌乳腺外科
  • 收稿日期:2019-08-06 出版日期:2020-04-01
  • 通信作者: 谭金祥

Related factors of local recurrence of breast cancer after breast-conserving surgery

Qi Xiao1, Yi Dou1, Wei Xiong1   

  • Received:2019-08-06 Published:2020-04-01
引用本文:

肖琪, 窦怡, 熊伟, 谭金祥. 乳腺癌保留乳房手术后局部复发的相关因素分析[J/OL]. 中华乳腺病杂志(电子版), 2020, 14(02): 124-128.

Qi Xiao, Yi Dou, Wei Xiong. Related factors of local recurrence of breast cancer after breast-conserving surgery[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2020, 14(02): 124-128.

虽然近年来中国保留乳房手术率不断上升,保留乳房手术已逐渐成为早期乳腺癌患者的主要手术方式之一,但与欧美发达国家相比,中国的保留乳房手术率仍较低。患者担心乳腺癌保留乳房手术后局部复发是影响保留乳房手术率提高的重要原因之一。大量文献对乳腺癌保留乳房手术后局部复发的相关因素进行了报道,笔者对近年来相关文献进行分析并综述。

[1]
Habermann EB, Abbott A, Parsons HM, et al. Are mastectomy rates really increasing in the United States? [J]. J Clin Oncol, 2010, 28(21): 3437-3441.
[2]
Del Turco MR, Ponti A, Bick U, et al. Quality indicators in breast cancer care [J]. Eur J Cancer, 2010, 46(13): 2344-2356.
[3]
Fan L, Strasser-Weippl K, Li JJ, et al. Breast cancer in China [J]. Lancet Oncol, 2014, 15(7): e279-e289.
[4]
Bao X, Sun K, Tian X, et al. Present and changing trends in surgical modalities and neoadjuvant chemotherapy administration for female breast cancer in Beijing, China: A 10-year (2006-2015) retrospective hospitalization summary report-based study [J]. Thorac Cancer, 2018, 9(6): 707-717.
[5]
Kong Y, Yang L, Tang H, et al. A nation-wide multicenter retrospective study of the epidemiological, pathological and clinical characteristics of breast cancer in situ in Chinese women in 1999 - 2008 [J]. PLoS One, 2013, 8(11): e8 1055.
[6]
Ordu C, Mcguire K, Alco G, et al. The prognostic impact of molecular subtypes and very young age on breast conserving surgery in early stage breast cancer [J]. Cureus, 2016, 8(6): e633.
[7]
Lertsithichai P, Sakulchairungreung B, Chirappapha P, et al. Effect of young age, positive margins, and triple negative status on disease recurrence after breast conserving therapy [J]. Gland Surg, 2016, 5(1): 15-23
[8]
Kim SW, Chun M, Han S, et al. Young age is associated with increased locoregional recurrence in node-positive breast cancer with luminal subtypes [J]. Cancer Res Treat, 2017, 49(2): 484-493.
[9]
Kim IK, Park S, Hwang H, et al. Clinical significance of age at the time of diagnosis among young breast cancer patients [J]. J Breast Cancer, 2011, 14(4): 314-321.
[10]
Goksu SS, Tastekin D, Arslan D, et al. Clinicopathologic features and molecular subtypes of breast cancer in young women (age ≤35) [J]. Asian Pac J Cancer Prev, 2014, 15(16): 6665-6668.
[11]
Wong FY, Tham WY, Nei WL, et al. Age exerts a continuous effect in the outcomes of Asian breast cancer patients treated with breast-conserving therapy [J]. Cancer Commun (Lond), 2018, 38(1): 39.
[12]
Foo CS, Su D, Chong CK, et al. Breast cancer in young Asian women: study on survival [J]. ANZ J Surg, 2005, 75(7): 566-572.
[13]
Erdem E, Alagol H. Results of breast conserving surgery in clinical stage Ⅰ-Ⅱ breast carcinoma [J]. Indian J Surg, 2009, 71(1): 29-34.
[14]
Shafik YS, Rafik H, Helmy M. Factors contributing to local recurrence after conservative breast surgery for early-stage breast cancer [J]. Egypt J Surg, 2018, 37(4): 429-439.
[15]
Wang L, Li J, Wang T, et al. Impact of clinical and pathological factors on local recurrence after breast-conserving treatment: CT-based localization for a tumor bed boost yielded better local control when compared with a surgical scar [J]. J Cancer, 2019, 10(3): 708-715.
[16]
Livi L, Paiar F, Saieva C, et al. Survival and breast relapse in 3834 patients with T1-T2 breast cancer after conserving surgery and adjuvant treatment [J]. Radiother Oncol, 2007, 82(3): 287-293.
[17]
Mirza NQ, Vlastos G, Meric F, et al. Predictors of locoregional recurrence among patients with early-stage breast cancer treated with breast-conserving therapy [J]. Ann Surg Oncol, 2002, 9(3): 256-265.
[18]
Litière S, Werutsky G, Fentiman IS, et al. Breast conserving therapy versus mastectomy for stage Ⅰ-Ⅱ breast cancer: 20 year follow-up of the EORTC 10801 phase 3 randomised trial [J]. Lancet Oncol, 2012, 13(4): 412-419.
[19]
Libson S, Koshenkov V, Rodgers S, et al. Breast conservation after neoadjuvant therapy for tumors ≥5 cm: A prospective cohort study [J]. Int J Surg Open, 2015, 1: 10-13.
[20]
Mazor AM, Mateo AM, Demora L, et al. Breast conservation versus mastectomy in patients with T3 breast cancers (> 5 cm): an analysis of 37,268 patients from the National Cancer Database [J]. Breast Cancer Res Treat, 2019, 173(2): 301-311.
[21]
Braunstein LZ, Taghian AG, Niemierko A, et al. Breast-cancer subtype, age, and lymph node status as predictors of local recurrence following breast-conserving therapy [J]. Breast Cancer Res Treat, 2016, 161(1): 173-179.
[22]
Elsayed M, Alhussini M, Basha A, et al. Analysis of loco-regional and distant recurrences in breast cancer after conservative surgery [J]. World J Surg Oncol, 2016, 14:144.
[23]
Dings PJ, Elferink MA, Strobbe LJ, et al. The prognostic value of lymph node ratio in node-positive breast cancer: A dutch nationwide population-based study [J]. Ann Surg Oncol, 2013, 20(8): 2607-2614.
[24]
Su S, Wang C, Wang X, et al. Prognostic value of combining lymph node ratio and number of positive lymph nodes in breast cancer: A population-based study [J]. Breast J, 2019, 25(5): 1020-1022.
[25]
Mittendorf EA, Buchholz TA, Tucker SL, et al. Impact of chemotherapy sequencing on local-regional failure risk in breast cancer patients undergoing breast-conserving therapy [J]. Ann Surg, 2013, 257(2): 173-179.
[26]
Yamazaki N, Wada N, Yamauchi C, et al. High expression of post-treatment Ki-67 status is a risk factor for locoregional recurrence following breast-conserving surgery after neoadjuvant chemotherapy [J]. Eur J Surg Oncol, 2015, 41(5): 617-624.
[27]
Mohammed RA, Martin SG, Mahmmod AM, et al. Objective assessment of lymphatic and blood vascular invasion in lymph node-negative breast carcinoma: findings from a large case series with long-term follow-up [J]. J Pathol, 2011, 223(3): 358-365.
[28]
中国抗癌协会乳腺癌专业委员会. 中国抗癌协会乳腺癌诊治指南与规范(2019年版) [J]. 中国癌症杂志,2019, 29(8): 609-679.
[29]
Goldhirsch A, Winer EP, Coates AS, et al. Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013 [J]. Ann Oncol, 2013, 24(9): 2206-2223.
[30]
Lowery AJ, Kell MR, Glynn RW, et al. Locoregional recurrence after breast cancer surgery: a systematic review by receptor phenotype [J]. Breast Cancer Res Treat, 2012, 133(3): 831-841.
[31]
Gangi A, Chung A, Mirocha J, et al. Breast-conserving therapy for triple-negative breast cancer [J]. JAMA Surg, 2014, 149(3): 252-258.
[32]
Mcguire A, Lowery AJ, Kell MR, et al. Locoregional recurrence following breast cancer surgery in the trastuzumab era: A systematic review by subtype [J]. Ann Surg Oncol, 2017, 24(11): 3124-3132.
[33]
Anderson SJ, Wapnir I, Dignam JJ, et al. Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in patients treated by breast-conserving therapy in five National Surgical Adjuvant Breast and Bowel Project protocols of node-negative breast cancer [J]. J Clin Oncol, 2009, 27(15): 2466-2473.
[34]
Pilewskie M, Morrow M. Margins in breast cancer: How much is enough? [J]. Cancer, 2018, 124(7): 1335-1341.
[35]
Fisher B, Bauer M, Margolese R, et al. Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer [J]. N Engl J Med, 1985, 312(11): 665-673.
[36]
Veronesi U, Volterrani F, Luini A, et al. Quadrantectomy versus lumpectomy for small size breast cancer [J]. Eur J Cancer, 1990, 26(6): 671-673.
[37]
Houssami N, Macaskill P, Marinovich ML, et al. Meta-analysis of the impact of surgical margins on local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy [J]. Eur J Cancer, 2010, 46(18): 3219-3232.
[38]
Azu M, Abrahamse P, Katz SJ, et al. What is an adequate margin for breast-conserving surgery? Surgeon attitudes and correlates [J]. Ann Surg Oncol, 2010, 17(2): 558-563.
[39]
Moran MS, Schnitt SJ, Giuliano AE, et al. Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages Ⅰ and Ⅱ invasive breast cancer [J]. Ann Surg Oncol, 2014, 21(3): 704-716.
[40]
Houssami N, Macaskill P, Marinovich ML, et al. The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: a meta-analysis [J]. Ann Surg Oncol, 2014, 21(3): 717-730.
[41]
Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials [J]. Lancet, 2005, 366(9503): 2087-2106.
[42]
Darby S, Mcgale P, Correa C, et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials [J]. Lancet, 2011, 378(9 804): 1707-1716.
[43]
Speers C, Pierce LJ. Postoperative radiotherapy after breast-conserving surgery for early-stage breast cancer: A review [J]. JAMA Oncol, 2016, 2(8): 1075-1082.
[44]
Polgár C, Fodor J, Major T, et al. Breast-conserving therapy with partial or whole breast irradiation: Ten-year results of the Budapest randomized trial [J]. Radiother Oncol, 2013, 108(2): 197-202.
[45]
Coles CE, Griffin CL, Kirby AM, et al. Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial [J]. Lancet, 2017, 390(10 099): 1048-1060.
[46]
Polgár C, Van Limbergen E, Pötter R, et al. Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: Recommendations of the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009) [J]. Radiother Oncol, 2010, 94(3): 264-273.
[47]
Vaidya JS, Wenz F, Bulsara M, et al. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial [J]. Lancet, 2014, 383(9917): 603-613.
[48]
Zhang L, Zhou Z, Mei X, et al. Intraoperative radiotherapy versus whole-breast external beam radiotherapy in early-stage breast cancer: A systematic review and meta-analysis [J]. Medicine (Baltimore), 2015, 94(27): e1143.
[49]
Gradishar WJ, Anderson BO, Balassanian R, et al. Breast cancer, version 4.2017, NCCN Clinical practice guidelines in oncology [J]. J Natl Compr Canc Netw, 2018, 16(3): 310-320.
[50]
Senkus E, Kyriakides S, Ohno S, et al. Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up [J]. Ann Oncol, 2015, 26 Suppl 5:v8-v30.
[51]
Francis PA, Pagani O, Fleming GF, et al. Tailoring adjuvant endocrine therapy for premenopausal breast cancer [J]. N Engl J Med, 2018, 379(2): 122-137.
[52]
Lippman ME. Endocrine adjuvant therapy for localized breast cancer [J]. N Engl J Med, 2018, 379(2): 193-194.
[53]
Wenners A, Berlin L, Alkatout I, et al. Clinical implications of first and multiple locoregional breast cancer recurrences [J]. Arch Gynecol Obstet, 2014, 292(1): 165-173.
[54]
Mamounas EP, Tang G, Liu Q. The importance of systemic therapy in minimizing local recurrence after breast-conserving surgery: the NSABP experience [J]. J Surg Oncol, 2014, 110(1): 45-50.
[55]
Bhatti AB, Jamshed A, Shah M, et al. Breast conservative therapy in Pakistani women: Prognostic factors for locoregional recurrence and overall survival [J]. J Cancer Res Ther, 2015, 11(2):300-304.
[56]
中国临床肿瘤学会指南工作委员会. 中国临床肿瘤学会(CSCO)乳腺癌诊疗指南2018.V1[M]. 北京:人民卫生出版社,2018.
[57]
Davies C, Pan H, Godwin J, et al. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial [J]. Lancet, 2013, 381(9869): 805-816.
[58]
Tovar JR, Zandonade E, Amorim MH. Factors associated with the incidence of local recurrences of breast cancer in women who underwent conservative surgery [J]. Int J Breast Cancer, 2014, 2014: 639 534.
[59]
Bellon JR, Guo H, Barry WT, et al. Local-regional recurrence in women with small node-negative, HER2-positive breast cancer: results from a prospective multi-institutional study (the APT trial) [J]. Breast Cancer Res Treat, 2019, 176(2): 303-310.
[60]
Curigliano G, Burstein HJ, Winer EP, et al. De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017 [J]. Ann Oncol, 2017, 28(8): 1 700-1 712.
[61]
Von Minckwitz G, Procter M, De Azambuja E, et al. Adjuvant pertuzumab and trastuzumab in early HER2-positive breast cancer [J]. N Engl J Med, 2017, 377(2): 122-131.
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