切换至 "中华医学电子期刊资源库"

中华乳腺病杂志(电子版) ›› 2019, Vol. 13 ›› Issue (06) : 362 -363. doi: 10.3877/cma.j.issn.1674-0807.2019.06.008

所属专题: 文献

综述

多巴胺受体在乳腺癌中的研究进展
林健1, 方敏1, 吴雅妮1, 刘超乾1, 苏东玮1, 于跃1, 李恒宇1, 盛湲1,()   
  1. 1. 200433 上海,第二军医大学附属长海医院甲状腺乳腺外科
  • 收稿日期:2018-03-01 出版日期:2019-12-01
  • 通信作者: 盛湲
  • 基金资助:
    国家自然科学基金青年项目(81502546); 第二军医大学精准医学转化应用研究专项(2017JZ37/2017JZ07)

Dopamine receptors in breast cancer

Jian Lin1, Min Fang1, Yani Wu1   

  • Received:2018-03-01 Published:2019-12-01
引用本文:

林健, 方敏, 吴雅妮, 刘超乾, 苏东玮, 于跃, 李恒宇, 盛湲. 多巴胺受体在乳腺癌中的研究进展[J/OL]. 中华乳腺病杂志(电子版), 2019, 13(06): 362-363.

Jian Lin, Min Fang, Yani Wu. Dopamine receptors in breast cancer[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2019, 13(06): 362-363.

多巴胺受体在调节人体生理功能中发挥重要作用,同时也与肿瘤的发生、发展关系密切。近年来,众多的研究发现多巴胺受体信号途径与乳腺癌的发生、发展和预后密切相关,多巴胺受体有可能成为靶向治疗乳腺癌的新靶点。笔者就多巴胺受体与乳腺癌的研究进展进行综述,以期给乳腺癌的防治带来新启发。

[1]
Beaulieu JM, Gainetdinov RR. The physiology, signaling, and pharmacology of dopamine receptors[J]. Pharmacol Rev,2011,63(1):182-217.
[2]
Gholipour N, Ohradanova-Repic A, Ahangari G. A novel report of MiR-4301 induces cell apoptosis by negatively regulating DRD2 expression in human breast cancer cells[J]. J Cell Biochem, 2018,119(8):6408-6417.
[3]
Andereggen L, Frey J, Andres RH, et al. 10-year follow-up study comparing primary medical vs. surgical therapy in women with prolactinomas[J]. Endocrine,2017,55(1):223-230.
[4]
Sarkar C, Chakroborty D, Chowdhury UR, et al. Dopamine increases the efficacy of anticancer drugs in breast and colon cancer preclinical models[J]. Clin Cancer Res,2008,14(8):2502-2510.
[5]
Costa R, Santa-Maria CA, Scholtens DM, et al. A pilot study of cabergoline for the treatment of metastatic breast cancer[J]. Breast Cancer Res Treat,2017,165(3):585-592.
[6]
Rondou P, Haegeman G, Van Craenenbroeck K. The dopamine D4 receptor: biochemical and signalling properties[J]. Cell Mol Life Sci,2010,67(12):1971-1986.
[7]
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2017[J]. CA Cancer J Clin,2017,67(1):7-30.
[8]
陈万青,孙可欣,郑荣寿,等. 2014年中国分地区恶性肿瘤发病和死亡分析[J]. 中国肿瘤,2018,27(1):1-14.
[9]
Minami K, Liu S, Liu Y, et al. Inhibitory effects of dopamine receptor D1 agonist on mammary tumor and bone metastasis[J]. Sci Rep,2017,7:45686.
[10]
Pornour M, Ahangari G, Hejazi SH, et al. New perspective therapy of breast cancer based on selective dopamine receptor D2 agonist and antagonist effects on MCF-7 cell line[J]. Recent Pat Anticancer Drug Discov,2015,10(2):214-223.
[11]
Wang S, Mou Z, Ma Y, et al. Dopamine enhances the response of sunitinib in the treatment of drug-resistant breast cancer: Involvement of eradicating cancer stem-like cells[J]. Biochem Pharmacol,2015,95(2):98-109.
[12]
Jin X, Zou B, Luo L, et al. Codelivery of thioridazine and doxorubicin using nanoparticles for effective breast cancer therapy[J]. Int J Nanomedicine,2016,11:4545-4552.
[13]
Li J, Yao QY, Xue JS, et al. Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer[J]. Acta Pharmacol Sin,2017,38(9):1282-1296.
[14]
Borcherding DC, Tong W, Hugo ER, et al. Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer[J]. Oncogene,2016,35(24):3103-3113.
[15]
Wang PS, Walker AM, Tsuang MT, et al. Dopamine antagonists and the development of breast cancer[J]. Arch Gen Psychiatry,2002,59(12):1147-1154.
[16]
Bushe CJ, Bradley AJ, Wildgust HJ, et al. Schizophrenia and breast cancer incidence: a systematic review of clinical studies[J]. Schizophr Res,2009,114(1-3):6-16.
[17]
Pornour M, Ahangari G, Hejazi SH, et al. Dopamine receptor gene (DRD1-DRD5) expression changes as stress factors associated with breast cancer[J]. Asian Pac J Cancer Prev,2014,15(23):10339-10343.
[18]
Akbari ME, Kashani FL, Ahangari G, et al. The effects of spiritual intervention and changes in dopamine receptor gene expression in breast cancer patients[J]. Breast Cancer,2016,23(6):893-900.
[19]
Bakhtou H, Olfatbakhsh A, Deezagi A, et al. The expression of dopamine receptors gene and their potential role in targeting breast cancer cells with selective agonist and antagonist drugs. Could it be the novel insight to therapy?[J]. Curr Drug Discov Technol, 2019,16(2):184-197.
[20]
盛湲,李恒宇. 从单细胞水平看肿瘤异质性[J/CD]. 中华乳腺病杂志(电子版),2014,8(6):6-12.
[21]
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell[J]. Nat Med,1997,3(7):730-737.
[22]
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation[J]. Cell,2011,144(5):646-674.
[23]
Ricardo S, Vieira AF, Gerhard R, et al. Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype[J]. J Clin Pathol,2011,64(11):937-946.
[24]
Sachlos E, Risueno RM, Laronde S, et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells[J]. Cell,2012,149(6):1284-1297.
[1] 李洋, 蔡金玉, 党晓智, 常婉英, 巨艳, 高毅, 宋宏萍. 基于深度学习的乳腺超声应变弹性图像生成模型的应用研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(06): 563-570.
[2] 河北省抗癌协会乳腺癌专业委员会护理协作组. 乳腺癌中心静脉通路护理管理专家共识[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 321-329.
[3] 刘晨鹭, 刘洁, 张帆, 严彩英, 陈倩, 陈双庆. 增强MRI 影像组学特征生境分析在预测乳腺癌HER-2 表达状态中的应用[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 339-345.
[4] 张晓宇, 殷雨来, 张银旭. 阿帕替尼联合新辅助化疗对三阴性乳腺癌的疗效及预后分析[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 346-352.
[5] 邱琳, 刘锦辉, 组木热提·吐尔洪, 马悦心, 冷晓玲. 超声影像组学对致密型乳腺背景中非肿块型乳腺癌的诊断价值[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 353-360.
[6] 程燕妮, 樊菁, 肖瑶, 舒瑞, 明昊, 党晓智, 宋宏萍. 乳腺组织定位标记夹的应用与进展[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 361-365.
[7] 涂盛楠, 胡芬, 张娟, 蔡海峰, 杨俊泉. 天然植物提取物在乳腺癌治疗中的应用[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 366-370.
[8] 朱文婷, 顾鹏, 孙星. 非酒精性脂肪性肝病对乳腺癌发生发展及治疗的影响[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 371-375.
[9] 周荷妹, 金杰, 叶建东, 夏之一, 王进进, 丁宁. 罕见成人肋骨郎格汉斯细胞组织细胞增生症被误诊为乳腺癌术后骨转移一例[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 380-383.
[10] 葛睿, 陈飞, 李杰, 李娟娟, 陈涵. 多基因检测在早期乳腺癌辅助治疗中的应用价值[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(05): 257-263.
[11] 高杰红, 黎平平, 齐婧, 代引海. ETFA和CD34在乳腺癌中的表达及与临床病理参数和预后的关系研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 64-67.
[12] 韩萌萌, 冯雪园, 马宁. 乳腺癌改良根治术后桡神经损伤1例[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 117-118.
[13] 张志兆, 王睿, 郜苹苹, 王成方, 王成, 齐晓伟. DNMT3B与乳腺癌预后的关系及其生物学机制[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 624-629.
[14] 王玲艳, 高春晖, 冯雪园, 崔鑫淼, 刘欢, 赵文明, 张金库. 循环肿瘤细胞在乳腺癌新辅助及术后辅助治疗中的应用[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 630-633.
[15] 赵林娟, 吕婕, 王文胜, 马德茂, 侯涛. 超声引导下染色剂标记切缘的梭柱型和圆柱型保乳区段切除术的效果研究[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 634-637.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?