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中华乳腺病杂志(电子版) ›› 2018, Vol. 12 ›› Issue (03) : 177 -181. doi: 10.3877/cma.j.issn.1674-0807.2018.03.010

所属专题: 文献

综述

循环肿瘤细胞在乳腺癌个体化诊治中的研究进展
郭瑢1, 吴炅1,()   
  1. 1. 200032 上海,复旦大学附属肿瘤医院乳腺外科
  • 收稿日期:2017-03-03 出版日期:2018-06-01
  • 通信作者: 吴炅

Circulating tumor cells for individualized diagnosis and treatment of breast cancer patients

Rong Guo1, Jiong Wu1()   

  • Received:2017-03-03 Published:2018-06-01
  • Corresponding author: Jiong Wu
引用本文:

郭瑢, 吴炅. 循环肿瘤细胞在乳腺癌个体化诊治中的研究进展[J/OL]. 中华乳腺病杂志(电子版), 2018, 12(03): 177-181.

Rong Guo, Jiong Wu. Circulating tumor cells for individualized diagnosis and treatment of breast cancer patients[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2018, 12(03): 177-181.

循环肿瘤细胞从实体肿瘤病灶中脱离进入血液循环,携带了肿瘤细胞的特性,并且随疾病进展发生着改变,为临床上相对无创地获取肿瘤细胞样本提供了独有的机遇与挑战。近年来,大量的研究探索将循环肿瘤细胞应用于乳腺癌临床决策中,肯定了其在各期乳腺癌疾病进展及预后预测中的作用。同时,富集及检测技术的发展,为利用循环肿瘤细胞数目及其分子生物学特性进行疾病进展监测、药物疗效评估、指导乳腺癌个体化治疗选择以及寻找药物治疗新靶点带来了希望。现就循环肿瘤细胞在乳腺癌治疗决策中的最新研究进展予以简要综述。

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