目的

对启东市2001～2007 年全人群女性乳腺癌登记病例进行生存率分析，为预后评价提供依据。

方法

858 例登记病例的生存（死亡）情况随访截止于2009 年12 月31 日。 用SURV3.01 软件计算观察生存率（OS）及相对生存率（RS）。

结果

女性乳腺癌患者1、3、5 年OS 分别为84.36% 、73.47% 、66.80% ，1、3、5 年RS 分别为85.40% 、76.26%和71.10% 。 15～34 岁、35～44 岁、45～54 岁、55～64 岁、65～74 岁及≥75 岁各年龄组的5 年RS 分别为34.98% 、80.86% 、72.64% 、60.68% 、82.45% 、67.91% 。 各年龄组观察生存率间的差异有统计学意义（χ²=53.93，P=0.00）。 2001～2007年启东市女性乳腺癌患者的5 年RS（71.10% ）比1972～1976 年及1987～1991 年的54.38%和61.28%均有显著提高。

结论

2001～2007 年启东市女性乳腺癌登记病例的总体生存率有较大的提高。

Objective

To analyze the survival rate of female breast cancer from the populationbased cancer registry data from 2001 to 2007 in Qidong in order to provide a basis for assessing the prognosis and treatment of this disease.

Methods

Eight hundred and fifty-eight registered cases were followed up until December 31， 2009.Cumulative observed survival rate （OS） and relative survival rate（RS） were calculated using SURV3.01 software developed by the Finnish Cancer Registry.

Results

The OS of female breast cancer patients at 1， 3 and 5 years was 84.36% ， 73.47% and 66.80% ，respectively； and the RS was 85.40% ， 76.26% and 71.10% ， respectively.The 5-year RS in patients aged 14—34 years， 35—44 years， 45—54 years， 55—64 years， 65—74 years and ≥75 years was 34.98% ， 80.86% ， 72.64% ， 60.68% ， 82.45% ， 67.91% and 71.10% ， respectively.There was a statistical difference in OS among the six age groups（χ² =53.93，P=0.00）.The 5-year RS of female breast cancer patients in 2001—2007 was 71.10% ， which was remarkably improved compared with that in 1972—1976 （54.38%） and 1987—1991 （61.28%） in Qidong.

Conclusions

The overall survival rate of female breast cancer of the registered cases in 2001-2007 in Qidong has been improved greatly.