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中华乳腺病杂志(电子版) ›› 2025, Vol. 19 ›› Issue (04) : 247 -252. doi: 10.3877/cma.j.issn.1674-0807.2025.04.010

综述

激素受体阳性乳腺癌的预后评估
刘纹延1, 马志军2,()   
  1. 1 810016 西宁,青海大学研究生院
    2 810001 西宁,青海大学附属医院肿瘤外科
  • 收稿日期:2025-04-06 出版日期:2025-08-01
  • 通信作者: 马志军
  • 基金资助:
    国家自然科学基金资助项目(82060485)

Prognostic evaluation of hormone receptor positive breast cancer

Wenyan Liu, Zhijun Ma()   

  • Received:2025-04-06 Published:2025-08-01
  • Corresponding author: Zhijun Ma
引用本文:

刘纹延, 马志军. 激素受体阳性乳腺癌的预后评估[J/OL]. 中华乳腺病杂志(电子版), 2025, 19(04): 247-252.

Wenyan Liu, Zhijun Ma. Prognostic evaluation of hormone receptor positive breast cancer[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2025, 19(04): 247-252.

激素受体阳性乳腺癌,包括Luminal A/B亚型,占所有乳腺癌病例的60%~70%,是最常见的乳腺癌类型。本综述系统分析了当前用于预测激素受体阳性乳腺癌患者预后的多维度评估体系,包括临床病理特征、分子标志物分析、液体活检技术以及免疫标志物等。通过整合这些多维度数据旨在优化个体化治疗方案,为激素受体阳性乳腺癌患者提供更精准的治疗策略。

图1 多维度评估体系指导HR阳性乳腺癌患者个体化治疗的临床应用路径 注:HR为激素受体;BMI为体质量指数,AR为雄激素受体,Ki-67为细胞增殖指数,P53为肿瘤蛋白p53,CEA为癌胚抗原,CA15-3为癌抗原15-3,CA-125为癌抗原125,CTC为循环肿瘤细胞,ctDNA为循环肿瘤DNA
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