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中华乳腺病杂志(电子版) ›› 2018, Vol. 12 ›› Issue (02) : 116 -119. doi: 10.3877/cma.j.issn.1674-0807.2018.02.011

所属专题: 文献

讲座

多环芳烃与乳腺癌的相关性
禚英杰1, 余之刚1,()   
  1. 1. 250033 济南,山东大学第二医院乳腺外科
  • 收稿日期:2016-08-19 出版日期:2018-04-01
  • 通信作者: 余之刚

Correlation between polycyclic aromatic hydrocarbons and breast cancer

Yingjie Zhuo1, Zhigang Yu1()   

  • Received:2016-08-19 Published:2018-04-01
  • Corresponding author: Zhigang Yu
引用本文:

禚英杰, 余之刚. 多环芳烃与乳腺癌的相关性[J/OL]. 中华乳腺病杂志(电子版), 2018, 12(02): 116-119.

Yingjie Zhuo, Zhigang Yu. Correlation between polycyclic aromatic hydrocarbons and breast cancer[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2018, 12(02): 116-119.

随着交通工具及现代工业的发展,多环芳烃(PAHs)在空气中的含量逐步增加。乳腺癌作为一种女性常见的恶性肿瘤,发病率逐年上升。部分病因学研究表明,PAHs等环境污染物与乳腺癌存在一定的相关性。PAHs进入机体后,不仅能被代谢解毒,而且也可经代谢而被活化,形成致癌物质。笔者主要从PAHs的体内代谢、关键酶和代谢产物方面进行文献整理,并对当前PAHs与乳腺癌相关性的研究进行总结,进一步探讨PAHs在乳腺癌发病中的作用,以期为乳腺癌的预防和治疗提供新途径。

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