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中华乳腺病杂志(电子版) ›› 2017, Vol. 11 ›› Issue (03) : 162 -165. doi: 10.3877/cma.j.issn.1674-0807.2017.03.008

综述

微小RNA 在人表皮生长因子受体2 阳性乳腺癌中的研究进展
苑晔1, 李曼1,()   
  1. 1.116003 大连医科大学附属第二医院肿瘤科
  • 收稿日期:2016-11-29 出版日期:2017-06-01
  • 通信作者: 李曼
  • 基金资助:
    国家自然科学基金应急管理项目(81650018);国家自然科学基金面上项目(81673762)

Research progress of microRNA in HER-2 positive breast cancer

Ye Yuan, Man Li()   

  • Received:2016-11-29 Published:2017-06-01
  • Corresponding author: Man Li
引用本文:

苑晔, 李曼. 微小RNA 在人表皮生长因子受体2 阳性乳腺癌中的研究进展[J/OL]. 中华乳腺病杂志(电子版), 2017, 11(03): 162-165.

Ye Yuan, Man Li. Research progress of microRNA in HER-2 positive breast cancer[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2017, 11(03): 162-165.

微小RNA(miRNA)是一种可调控mRNA 表达的单链小分子RNA,其异常表达与诸多肿瘤的发生、发展密切相关。 研究表明,miRNA 在HER-2 阳性乳腺癌中扮演着重要角色,为其临床诊断及治疗提供了新思路。 笔者就miRNA 作为一种新的分子标志物在HER-2 阳性乳腺癌中的研究进展作一综述。

表1 HER-2 阳性乳腺癌相关miRNA 的表达及作用
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