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中华乳腺病杂志(电子版) ›› 2012, Vol. 06 ›› Issue (06) : 681 -687. doi: 10.3877/cma. j. issn.1674-0807.2012.06.012

讲座

Notch3 的表达与乳腺癌发生发展的关系
陈春发1, 豆晓伟1, 张国君1,()   
  1. 1.515041 广东汕头,汕头大学医学院附属肿瘤医院乳腺中心;汕头大学医学院肿瘤研究中心
  • 收稿日期:2012-09-04 出版日期:2012-12-01
  • 通信作者: 张国君
  • 基金资助:
    国家自然科学基金资助项目(30973377)国家重点基础研究发展计划(973)(2011CB70770)

Correlation of Notch3 expression and the development of breast cancer

Chun-fa CHEN, Xiao-wei DOU, Guo-jun ZHANG()   

  • Received:2012-09-04 Published:2012-12-01
  • Corresponding author: Guo-jun ZHANG
引用本文:

陈春发, 豆晓伟, 张国君. Notch3 的表达与乳腺癌发生发展的关系[J/OL]. 中华乳腺病杂志(电子版), 2012, 06(06): 681-687.

Chun-fa CHEN, Xiao-wei DOU, Guo-jun ZHANG. Correlation of Notch3 expression and the development of breast cancer[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2012, 06(06): 681-687.

图1 Notch3 与Notch1/2 的结构差异 Notch3 结构下方的红色标记显示主要的不同区域,问号表明有争议的转录激活结构域[5];EGF-like:表皮生长因子样;LNR:Lin-Notch 重复序列;TM:跨膜区;RAM:接近胞膜区;ANK repeats:锚蛋白重复区域;TAD:转录激活结构域;PEST:脯氨酸-谷氨基酸-丝氨酸-苏氨酸
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