Abstract:

Objective

To evaluate the application value of fiberoptic ductoscopy in the treatment of intraductal occupying lesions with nipple discharge.

Methods

From September 2005 to December 2009 a total of 523 nipple discharge patients were examined using fiberoptic ductoscopy （FDS） in our hospital，among them 209 patients were found suffering intraductal space occupying lesions with nipple discharge，with diagnostic rate of 39.96% .Of the 209 patients， 193 had benign lesions and were treated with ductoscopically guided duct excision， and 16 patients had malignant lesions， including intraductal papilloma canceration in 6 cases， ductal carcinoma in situ in 3 cases， infiltrating duct carcinoma in 6 cases and intraductal papilloma with calcification， severe atypical hyperplasia of breast adenosis and local canceration in 1 case， and were managed with breast conserving surgery in 5 cases， simple mastectomy in 3， modified radical mastectomy in 4 and modified radical mastectomy plus immediate prosthesis implantation in 4.FDS plus probe location method was used for all operations.All patients were pathologically confirmed.The follow-up time was 5—56 months with median time of 25 months.

Results

The 193 patients with benign lesions were all cured， and the follow-up showed that except 2 patients lost to followup， the rest had no recurrence.For the 16 patients with malignant lesions， no recurrence， metastasis or death was found.

Conclusions

FDS is of clinical value in diagnosing intraductal occupying lesions with nipple discharge， and help to obtain accurate location and satisfactory therapeutic effect.

Key words: endoscopy, nipple discharge, breast intraductal occupying lesions