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中华乳腺病杂志(电子版) ›› 2024, Vol. 18 ›› Issue (05) : 292 -296. doi: 10.3877/cma.j.issn.1674-0807.2024.05.007

综 述

多基因检测对激素受体阳性、HER-2阴性乳腺癌新辅助化疗疗效预测的研究进展
王聪1, 李云涛2,(), 唐甜甜2, 王鑫蕊3, 吕鑫4, 范志刚4   
  1. 1.061000 沧州市人民医院乳腺中心
    2.050035 石家庄,河北医科大学第四医院乳腺中心
    3.067000 承德市中心医院甲乳直肠外科
    4.056004 邯郸,河北工程大学附属医院乳腺外科
  • 收稿日期:2023-12-01 出版日期:2024-10-01
  • 通信作者: 李云涛

Multigene panel testing for efficacy prediction of neoadjuvant chemotherapy in hormonal receptor-positive and HER-2-negative breast cancer

Cong Wang, Yuntao Li(), Tiantian Tang, Xinrui Wang, Xin Lv, Zhigang Fan   

  • Received:2023-12-01 Published:2024-10-01
  • Corresponding author: Yuntao Li
引用本文:

王聪, 李云涛, 唐甜甜, 王鑫蕊, 吕鑫, 范志刚. 多基因检测对激素受体阳性、HER-2阴性乳腺癌新辅助化疗疗效预测的研究进展[J]. 中华乳腺病杂志(电子版), 2024, 18(05): 292-296.

Cong Wang, Yuntao Li, Tiantian Tang, Xinrui Wang, Xin Lv, Zhigang Fan. Multigene panel testing for efficacy prediction of neoadjuvant chemotherapy in hormonal receptor-positive and HER-2-negative breast cancer[J]. Chinese Journal of Breast Disease(Electronic Edition), 2024, 18(05): 292-296.

目前,多基因检测技术在激素受体(HR)阳性、HER-2 阴性早期乳腺癌辅助治疗中的应用可以帮助筛选出低复发风险的人群豁免化疗,而且研究者开始探索多基因检测技术在筛选HR 阳性、HER-2 阴性早期乳腺癌新辅助化疗获益人群中的应用。 因此,本文总结了目前常见的多基因检测技术,如21 基因检测、70 基因检测、50 基因检测、EndoPredict 评分以及乳腺癌指数在HR 阳性、HER-2 阴性早期乳腺癌新辅助化疗中的临床研究及其临床应用的意义和可行性,以期为HR 阳性、HER-2 阴性早期乳腺癌新辅助治疗的选择提供更多的参考技术。

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