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中华乳腺病杂志(电子版) ›› 2023, Vol. 17 ›› Issue (04) : 243 -249. doi: 10.3877/cma.j.issn.1674-0807.2023.04.007

综述

乳腺癌芳香化酶抑制剂相关肌肉骨骼不良反应的研究进展
王青青, 耿翠芝, 苏晓雨, 彭玉晓, 秦明祎, 刘风侠()   
  1. 050017 石家庄,河北医科大学第四医院护理部
    050017 石家庄,河北医科大学第四医院乳腺中心
    050017 石家庄,河北医科大学第四医院血液内科
  • 收稿日期:2021-07-16 出版日期:2023-08-01
  • 通信作者: 刘风侠

Aromatase inhibitor-induced musculoskeletal adverse reactions in breast cancer patients

Qingqing Wang, Cuizhi Geng, Xiaoyu Su   

  • Received:2021-07-16 Published:2023-08-01
引用本文:

王青青, 耿翠芝, 苏晓雨, 彭玉晓, 秦明祎, 刘风侠. 乳腺癌芳香化酶抑制剂相关肌肉骨骼不良反应的研究进展[J/OL]. 中华乳腺病杂志(电子版), 2023, 17(04): 243-249.

Qingqing Wang, Cuizhi Geng, Xiaoyu Su. Aromatase inhibitor-induced musculoskeletal adverse reactions in breast cancer patients[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2023, 17(04): 243-249.

芳香化酶抑制剂是绝经后激素受体阳性女性乳腺癌患者内分泌治疗的一线药物,对于改善患者的生存有重大意义,但是芳香化酶抑制剂相关的肌肉骨骼不良反应常常使得患者的用药依从性降低,放弃内分泌治疗,进而导致复发风险增加。本文旨在介绍乳腺癌患者应用芳香化酶抑制剂期间产生的肌肉骨骼症状,包括芳香化酶抑制剂相关的骨关节痛和骨丢失,对其危险因素、评估方法和干预措施等进行综述。

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