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中华乳腺病杂志(电子版) ›› 2021, Vol. 15 ›› Issue (05) : 307 -310. doi: 10.3877/cma.j.issn.1674-0807.2021.05.007

综述

黄腐酚抗乳腺癌作用机制的研究进展
郭亚楠1, 郭文静2, 蒋兵1, 郭红云3, 王涛3, 张永东3, 苏海翔3,()   
  1. 1. 730000 兰州,甘肃中医药大学基础医学院中西医结合专业教研室
    2. 730000 兰州,甘肃中医药大学基础医学院中西医结合专业教研室;730000 兰州,甘肃省中医药研究中心
    3. 730050 兰州,甘肃省肿瘤医院转化医学研究中心
  • 收稿日期:2020-08-18 出版日期:2021-10-01
  • 通信作者: 苏海翔
  • 基金资助:
    国家自然科学基金青年基金资助项目(81803779); 甘肃省中医药研究中心2020年专项开放课题(zyzx-2020-zx1); 甘肃省中医药管理局科研课题(GKZ-2015-9)

Anti­proliferative mechanism of xanthohumol in breast cancer

Yanan Guo1, Wenjing Guo2, Bing Jiang1   

  • Received:2020-08-18 Published:2021-10-01
引用本文:

郭亚楠, 郭文静, 蒋兵, 郭红云, 王涛, 张永东, 苏海翔. 黄腐酚抗乳腺癌作用机制的研究进展[J]. 中华乳腺病杂志(电子版), 2021, 15(05): 307-310.

Yanan Guo, Wenjing Guo, Bing Jiang. Anti­proliferative mechanism of xanthohumol in breast cancer[J]. Chinese Journal of Breast Disease(Electronic Edition), 2021, 15(05): 307-310.

黄腐酚是啤酒花中主要的含异戊二烯基类黄酮,具有多种生物学作用,可通过促进细胞凋亡、阻滞肿瘤细胞周期、抑制肿瘤细胞侵袭迁移、抑制肿瘤细胞增殖、抑制芳香化酶的活性、调节机体免疫功能和抑制ER等机制参与调控肿瘤的发生和发展。笔者对有关黄腐酚治疗乳腺癌的基础研究进行综述,以探讨其在乳腺癌临床治疗中的应用前景。

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