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中华乳腺病杂志(电子版) ›› 2021, Vol. 15 ›› Issue (01) : 43 -45. doi: 10.3877/cma.j.issn.1674-0807.2021.01.008

所属专题: 文献

综述

长链非编码RNA在三阴性乳腺癌中的作用
王海瑞1, 汤琦1, 王月1, 李析胤1, 刘莉花1, 王淋1, 李云芬1, 聂建云1,()   
  1. 1. 650118 云南省肿瘤医院乳腺外科
  • 收稿日期:2019-09-24 出版日期:2021-02-01
  • 通信作者: 聂建云
  • 基金资助:
    国家自然科学基金资助项目(81760480)

Role of long non-coding RNA in triple negative breast cancer

Hairui Wang1, Qi Tang1, Yue Wang1   

  • Received:2019-09-24 Published:2021-02-01
引用本文:

王海瑞, 汤琦, 王月, 李析胤, 刘莉花, 王淋, 李云芬, 聂建云. 长链非编码RNA在三阴性乳腺癌中的作用[J]. 中华乳腺病杂志(电子版), 2021, 15(01): 43-45.

Hairui Wang, Qi Tang, Yue Wang. Role of long non-coding RNA in triple negative breast cancer[J]. Chinese Journal of Breast Disease(Electronic Edition), 2021, 15(01): 43-45.

三阴性乳腺癌(TNBC)作为乳腺癌恶性程度高、异型性强的一类亚型,找到其有效作用靶点是亟待解决的问题。长链非编码RNA(lncRNA)在TNBC的发生过程中起重要的调控作用,有希望成为临床化疗反应新型预测分子。笔者介绍了lncRNA参与调控TNBC细胞增殖、侵袭、转移及肿瘤干性相关信号通路的作用机制和功能研究,并探讨了lncRNA作为TNBC治疗靶点及诊断和预后的生物标志物的潜力。

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