切换至 "中华医学电子期刊资源库"

中华乳腺病杂志(电子版) ›› 2007, Vol. 01 ›› Issue (01) : 52 -56. doi: 10.3877/cma.j.issn.1674-0807.2007.01.017

综述

BCAR1/p130Cas 蛋白与乳腺癌抗雌激素药物耐药的相关研究
路洪超1, 耿翠芝1   
  1. 1.050011 石家庄,河北医科大学第四医院外一科
  • 收稿日期:2006-09-15 出版日期:2007-01-25

Association of BCAR1/p130Cas protein and breast cancer antiestrogen resistance

Hong-chao Lu, Cui-zhi Geng   

  • Received:2006-09-15 Published:2007-01-25
引用本文:

路洪超, 耿翠芝. BCAR1/p130Cas 蛋白与乳腺癌抗雌激素药物耐药的相关研究[J/OL]. 中华乳腺病杂志(电子版), 2007, 01(01): 52-56.

Hong-chao Lu, Cui-zhi Geng. Association of BCAR1/p130Cas protein and breast cancer antiestrogen resistance[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2007, 01(01): 52-56.

[1]
King R J, William L.McGuire Memorial Symposium.Estrogen and progestin effects in human breast carcinogenesis[J].Breast Cancer Res Treat,1993,27(1 -2) :3 -15.
[2]
Beato M, Sanchez-Pacheco A.Interaction of steroid hormone receptors with the transcription initiation complex[J].Endocr Rev,1996,17(6):587-609.
[3]
Foekens J A, Rio M C,Seguin P,etal.Prediction of relapse and survival in breast cancer patients by pS2 protein status[J].Cancer Res,1990,50(13):3832-3837.
[4]
Clarke R B,Howell A, Potten C S, et al.Dissociation between steroid receptor expression and cell proliferation in the human breast[J].Cancer Res,1997,57(22) :4987 -4991.
[5]
Jordan V C.Molecular mechanisms of antiestrogen action in breast cancer[J].Breast Cancer Res Treat,1994,31(1) :41 -52.
[6]
Katzenellenbogen B S,Montano M M, Ekena K,etal.McGuire Memorial Lecture.Antiestrogens:mechanisms of action and resistance in breast cancer[J].Breast Cancer Res Treat,1997,44(1) :23 -38.
[7]
Early Breast Cancer Trialists'Collaborative Group.Tamoxifen for early breast cancer:an overview of the randomised trials[J].Lancet,1998,351(9114):1451-1467.
[8]
Jaiyesimi I A, Buzdar A U, Decker D A,etal.Use of tamoxifen for breast cancer:twenty-eight years later[J].J Clin Oncol,1995,13(2) :513-529.
[9]
Foekens J A, Schmitt M, Van Putten W L, etal.Plasminogen activator inhibitor-1 and prognosis in primary breast cancer[J].J Clin Oncol,1994,12(8):1648 - 1658.
[10]
Johnston S R, Haynes B P, Smith I E, etal.Acquired tamoxifen resistance in human breast cancer and reduced intra-tumoral drug concentration [J].Lancet,1993,342(8886 -8887) :1521 -1522.
[11]
Murphy L C, Hilsenbeck S G, Dotzlaw H,etal.Relationship of clone 4 estrogen receptor variant messenger RNA expression to some known prognostic variables in human breast cancer[J].Clin Cancer Res 1995,1(2) :155 -159.
[12]
Dorssers L C, Van Agthoven T, Sieuwerts A M.Genetic mechanisms involved in progression to hormone independence of human breast cancer[M]//Berns P M, Romijn J C, Schroeder F H.Mechanisms of progression to hormone-independent growth of breast and prostatic cancer.Carnforth (U.K.):Parthenon Publishing Group Ltd, 1991:169 -182.
[13]
Clarke R, Thompson E W, Leonessa F, etal.Hormone resistance, invasiveness, and metastatic potential in breast cancer[J].Breast Cancer Res Treat,1993,24(3) :227 -239.
[14]
Brinkman A, van der Flier S, Kok E M, etal.BCAR1, a human homologue of the adaptor protein p130Cas, and antiestrogen resistance in breast cancer cells[J].J Natl Cancer Inst,2000,92(2):112-120.
[15]
Chan C M,Dowsett M.A novel estrogen receptor variant mRNA lacking exons 4 to 6 in breast carcinoma[J].J Steroid Biochem Mol Biol,1997,62(5 -6) :419 -430.
[16]
Dowsett M, Daffada A, Chan C M, etal.Oestrogen receptor mutants and variants in breast cancer[J].Eur J Cancer,1997,33(8) :1177 -1183.
[17]
Dorssers L C,Van Agthoven T,Dekker A,etal.Induction of antiestrogen resistance in human breast cancer cells by random insertional mutagenesis using defective retroviruses:identification of bcar-1, a common integration site[J].Mol Endocrinol,1993,7(7):870 - 878.
[18]
Dorssers L C, Veldscholte J.Identification of a novel breast cancer anti estrogen resistance (BCAR2) locus by cell fusion mediated gene transfer in human breast cancer cells[J].Int J Cancer,1997,72(4):700 -705.
[19]
van der Flier S, Brinkman A, Look M P, etal.Bcarl/p130Cas protein and primary breast cancer:prognosis and response to tamoxifen treatment[J].J Natl Cancer Inst,2000,92(2) :120 -127.
[20]
Jordan V C.How Is Tamoxifen's Action Subverted[J]?Journal of the National Cancer Institute,2000,92(2):92 - 94.
[21]
Takaya Gotoh, Xuejun Tian, Larry A, etal.Feig p130Cas Regulates the Activity of AND-34, a Novel Ral, Rapl, and R-Ras Guanine Nucleotide Exchange Factor[J].J Biol Chem,2000,275(39):30118 -30123.
[22]
Paul J.Ruest, Nah-Young Shin,Thomas R.Polte,et al.Mechanisms of CAS Substrate Domain Tyrosine Phosphorylation by FAK and Src[J].Molecular and Cellular Biology,2001,21(22) :7641-7652.
[23]
Scibelli A, d'Angelo D, Pelagalli A,etal.Expression levels of the focal adhesion-associated proteins paxillin and p130CAS in canine and feline mammary tumors[J].Vet Res,2003,34(2) :193-202.
[24]
de Jong R, van Wijk A, Haataja L,etal.BCR/ABLinduced leukemogenesis causes phosphorylation of Hefl and its association with Crkl[J].J Biol Chem,1997,272(51) :32649 -32655.
[25]
Zhang X A, He B, Zhou B,etal.Requirement of the p130CAS-Crk coupling for metastasis suppressor KAI1/CD82-mediated inhibition of cell migration[J].J Biol Chem,2003,278(29) :27319 -27328.
[26]
Cowell L N, Graham J D, Bouton A H,etal.Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway[J].Oncogene,2006,26:
[27]
Burnham M R, Harte M T, Richardson A,etal.The identification of p130cas-binding proteins and their role in cellular transformation [J].Oncogene, 1996,12(11) :2467 -2472.
[28]
Harbeck N, Schmitt M, Kates R E,etal.Clinical utility of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 determination in primary breast cancer tissue for individualized therapy con cepts[J].Clin Breast Cancer,2002,3(3):196-200.
[29]
Dorssers L C J, Grebenchtchikov N, Brinkman A, et al.Application of a newly developed ELISA for BCAR1 protein for prediction of clinical benefit of tamoxifen therapy in patients with advanced breast cancer[J].Clin Chem,2004,50:1445-1447.
[1] 李洋, 蔡金玉, 党晓智, 常婉英, 巨艳, 高毅, 宋宏萍. 基于深度学习的乳腺超声应变弹性图像生成模型的应用研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(06): 563-570.
[2] 河北省抗癌协会乳腺癌专业委员会护理协作组. 乳腺癌中心静脉通路护理管理专家共识[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 321-329.
[3] 刘晨鹭, 刘洁, 张帆, 严彩英, 陈倩, 陈双庆. 增强MRI 影像组学特征生境分析在预测乳腺癌HER-2 表达状态中的应用[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 339-345.
[4] 张晓宇, 殷雨来, 张银旭. 阿帕替尼联合新辅助化疗对三阴性乳腺癌的疗效及预后分析[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 346-352.
[5] 邱琳, 刘锦辉, 组木热提·吐尔洪, 马悦心, 冷晓玲. 超声影像组学对致密型乳腺背景中非肿块型乳腺癌的诊断价值[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 353-360.
[6] 程燕妮, 樊菁, 肖瑶, 舒瑞, 明昊, 党晓智, 宋宏萍. 乳腺组织定位标记夹的应用与进展[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 361-365.
[7] 涂盛楠, 胡芬, 张娟, 蔡海峰, 杨俊泉. 天然植物提取物在乳腺癌治疗中的应用[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 366-370.
[8] 朱文婷, 顾鹏, 孙星. 非酒精性脂肪性肝病对乳腺癌发生发展及治疗的影响[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 371-375.
[9] 韩萌萌, 冯雪园, 马宁. 乳腺癌改良根治术后桡神经损伤1例[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 117-118.
[10] 高杰红, 黎平平, 齐婧, 代引海. ETFA和CD34在乳腺癌中的表达及与临床病理参数和预后的关系研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 64-67.
[11] 张志兆, 王睿, 郜苹苹, 王成方, 王成, 齐晓伟. DNMT3B与乳腺癌预后的关系及其生物学机制[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 624-629.
[12] 王玲艳, 高春晖, 冯雪园, 崔鑫淼, 刘欢, 赵文明, 张金库. 循环肿瘤细胞在乳腺癌新辅助及术后辅助治疗中的应用[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 630-633.
[13] 赵林娟, 吕婕, 王文胜, 马德茂, 侯涛. 超声引导下染色剂标记切缘的梭柱型和圆柱型保乳区段切除术的效果研究[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 634-637.
[14] 曹能琦, 张恒, 郑立锋, 陶庆松, 嵇振岭. Ad-Hoc 自裁剪补片用于造口旁疝Sugarbaker 修补术[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 620-623.
[15] 马东扬, 李斌, 陆安清, 王光华, 雷文章, 宋应寒. Gilbert 与单层补片腹膜前疝修补术疗效的随机对照研究[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 629-633.
阅读次数
全文


摘要