Abstract:

Objective

To investigate the influential factors of postoperative drainage time for breast cancer patients and explore the appropriate treatment and nursing scheme to shorten catheterization time.

Methods

We retrospectively analyzed the clinicopathological data of 210 patients pathologically diagnosed with breast cancer who underwent modified radical mastectomy and intraoperative drainage from July 2013 to September 2014 in the Affiliated Hospital of Guangdong Medical College. Totally 23 factors including body mass index(BMI), number of lymph nodes, number of tumors, hypertension, diabetes, fibrinogen, white blood cells, red blood cells, preoperative chemotherapy were analyzed to detect their influence on postoperative drainage time in breast cancer patients. Univariate analysis was performed using t test and analysis of variance;multivariate analysis was conducted using Logistic regression.

Results

Univariate analysis showed that postoperative drainage time presented a statistically significant difference in the patients with different body mass index, tumor size,systolic blood pressure,clotting time,fibrinogen,white blood cell count,number of tumors,clinical stage, subcutaneous effusion, lymphedema and diabetic combination (t=-4.659, t=-1.983, F=5.268, t=3.105, F=7.238, t=-2.571, t=2.984, F=8.650, t=-4.506, t=-5.380, t=-2.219; all P＜0.050). Logistic regression showed that BMI, fibrinogen, white blood cell count, subcutaneous hydrops and lymphedema were significantly correlated with postoperative drainage time (OR=1.403, 0.335, 1.262, 4.554,9.559,all P＜0.050).

Conclusion

The increased BMI and white blood cell count, decreased fibrinogens, and the development of subcutaneous hydrops and lymphedema would increase postoperative drainage time, affecting the adjuvant therapy after modified radical mastectomy of breast cancer.

Key words: Breast neoplasms, Mastectomy, modified radical, Drainage