Abstract:
Objective
To study the clinical value of sentinel lymph node biopsy (SLNB) in breast cancer operation.
Methods
SLNB with methylene blue stain was performed in 42 breast cancer patients.Sentinel lymph node(SLN) negative patients by intraoperative frozen sections were grouped and treated with partial axillary lymph node dissection (PALND) and total axillary lymph node dissection (TALND).Postoperative complications and survival were studied and compared between the two groups.
Results
SLNs were successfully identified in 41 of 42 (97.6%) patients,and the false negative rate was 14.3%. The PALND group had lower incidence of postoperative complications than TALND group, with statistical difference (P ＜0.05). But there was no statistical difference in total survival rate between the two groups (P ＞0. 05).
Conclusion
SLNB can accurately predict the axillary lymph node status of breast cancer, and decrease the extension of surgery and postoperative complications in patients with breast cancer.
Key words:
Breast neoplasms,
Sentinel lymph node,
Biopsy
De-hai XIONG, Shi-de LIU, Xian-zhang CHEN, Tian-jin CHEN. Application value of sentinel lymph node biopsy with methylene blue staining in breast cancer operation[J]. Chinese Journal of Breast Disease(Electronic Edition), 2008, 02(03): 18-20.