Application of free dermal fat graft in breast conserving surgery

doi:10.3877/cma.j.issn.1674-0807.2021.02.003

Abstract

Abstract:

Objective

To evaluate the feasibility and efficacy of free dermal fat graft (FDFG) in breast conserving surgery (BCS).

Methods

A retrospective analysis was performed on the clinicopathological data and follow-up results of 39 patients who underwent FDFG-assisted BCS in the Liuzhou People’s Hospital from July 2016 to December 2019. Postoperative complications and appearance of the breast were evaluated.

Results

The median weight of FDFG in 39 patients was 98 g (76-135 g), the median weight of removed breast tissue was 81 g (60-114 g) and the median operative time was 245 min (215-305 g). All the FDFG survived. The incidence of postoperative complications was 12.8% (5/39), including 2 cases of fat liquefaction, 1 case of fat liquefaction combined with incision necrosis and infection, 1 case of hematoma and 1 case of poor incision healing at the abdominal wall donor site. The objective and subjective evaluation of postoperative breast appearance was excellent in 35 cases (89.7%) and 36 cases (92.3%), respectively. All patients were followed up for 2 to 43 months, median 24 months. One patient had local recurrence, 5 patients had distant metastasis and no death occurred.

Conclusion

The application of FDFG in BCS is feasible, with potentials in increasing the breast-conserving rate and improving cosmetic outcome.

Key words: Breast neoplasms, Mammaplasty, Surgical flaps, Dermis, Adipose tissue

Jiapeng Huang, Yaqiang Zhuang, Tao Zhou, Yiming Cao, Defei Wei, Qingmei Shi. Application of free dermal fat graft in breast conserving surgery[J]. Chinese Journal of Breast Disease(Electronic Edition), 2021, 15(02): 77-81.

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References 16

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临床病理特征		例数	构成比(%)
年龄
	≤35岁	9	23
	36～50岁	22	56
	>50岁	8	21
肿瘤位置
	内上象限	16	41
	外上象限	11	28
	内下象限	3	8
	外下象限	6	15
	乳头乳晕区	3	8
TNM分期
	Ⅰ期	13	33
	Ⅱ期	9	23
	Ⅲ_A期(限T_1-2N₂M₀)	17	44
病理类型
	浸润性非特殊癌	38	97
	化生癌	1	3
组织学分级
	1级	1	3
	2级	32	82
	3级	6	15
分子分型
	luminal A	12	31
	luminal B	20	51
	HER-2阳性	5	13
	三阴性	2	5

临床病理特征		例数	构成比(%)
年龄
	≤35岁	9	23
	36～50岁	22	56
	>50岁	8	21
肿瘤位置
	内上象限	16	41
	外上象限	11	28
	内下象限	3	8
	外下象限	6	15
	乳头乳晕区	3	8
TNM分期
	Ⅰ期	13	33
	Ⅱ期	9	23
	Ⅲ_A期(限T_1-2N₂M₀)	17	44
病理类型
	浸润性非特殊癌	38	97
	化生癌	1	3
组织学分级
	1级	1	3
	2级	32	82
	3级	6	15
分子分型
	luminal A	12	31
	luminal B	20	51
	HER-2阳性	5	13
	三阴性	2	5

手术资料	中位数	范围
切除乳腺组织质量(g)	81	60～114
游离真皮脂肪瓣质量(g)	98	76～135
手术总时间(min)	245	215～305
整形时间(min)	80	55～100
出血量(ml)	75	50～110

手术资料	中位数	范围
切除乳腺组织质量(g)	81	60～114
游离真皮脂肪瓣质量(g)	98	76～135
手术总时间(min)	245	215～305
整形时间(min)	80	55～100
出血量(ml)	75	50～110

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