Clinical study of vacuum-assisted biopsy for benign breast phyllodes tumor

doi:10.3877/cma.j.issn.1674-0807.2016.05.008

Abstract

Abstract:

Objective

To investigate the efficacy and safety of ultrasound-guided vacuum-assisted minimally invasive treatment for benign breast phyllodes tumor.

Methods

We enrolled 42 female patients with benign breast phyllodes tumor (diameter≤30 mm) treated in Fuxing Hospital, Capital Medical University from January 2009 to January 2011 by random number table for a prospective study. According to the patients'will,they were divided into 2 groups: minimally invasive group (21 cases) treated by ultrasound-guided vacuumassisted minimally invasive biopsy system, and control group (21 cases) treated by conventional local resection. Because of non-normal distribution, the parameters including operative time, blood loss and wound length were analyzed using Mann-Whitney test. The cases of postoperative infection, bleeding, bruising and local recurrence between two groups were compared using χ² test.

Results

The operative time, blood loss and wound length in minimally invasive group were superior to those in control group [(28.57±5.04) min vs(37.62±10.44) min, (20.00±9.49) ml vs (31.90±14.70) ml, (4.00±0.89) mm vs (20.00±4.47) mm],and the differences were statistically significant (Z = -2.896,-2.739,-5.650, all P＜0.050). After operation, there was 1 patient with postoperative infection, 1 with bleeding, 2 with bruising and 4 with local recurrence in minimally invasive group, 4, 3, 4, 2 in control group, respectively, indicating no significant difference (χ²=0.908,0.276,0.194,0.194, all P＞0.050). All patients in minimally invasive group were satisfactory with the appearance of breast (100%, 21/21), 15 in control group (71.4%, 15/21), and the difference was statistically significant (χ²=0.908, P=0.027).

Conclusion

For benign breast phyllodes with tumor diameter ≤30 mm, ultrasound-guided vacuum-assisted minimally invasive biopsy system has the advantages of precise resection, less trauma, rapid recovery and better cosmetic results over conventional local resection.

Key words: Breast neoplasms, Surgical procedures, minimally invasive, Biopsy

Xin Li, Chengyu Luo, Hailian Li, Zhimiao Cui, Baoyin Liu, Yufei Duan, Yi Ding. Clinical study of vacuum-assisted biopsy for benign breast phyllodes tumor[J]. Chinese Journal of Breast Disease(Electronic Edition), 2016, 10(05): 291-294.

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References 25

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组别	例数	手术时间(min)	术中出血量(ml)	伤口长度(mm)
微创组	21	28.57±5.04	20.00±9.49	4.00±0.89
对照组	21	37.62±10.44	31.90±14.70	20.00±4.47
Z值		-2.896	-2.739	5.650
P值		0.004	0.006	＜0.001

组别	例数	手术时间(min)	术中出血量(ml)	伤口长度(mm)
微创组	21	28.57±5.04	20.00±9.49	4.00±0.89
对照组	21	37.62±10.44	31.90±14.70	20.00±4.47
Z值		-2.896	-2.739	5.650
P值		0.004	0.006	＜0.001

组别	例数	感染	出血	瘀斑	局部复发
微创组	21	1	1	2	4
对照组	21	4	3	4	2
χ²值		0.908	0.276	0.194	0.194
P值		0.341	0.599	0.659	0.659

组别	例数	感染	出血	瘀斑	局部复发
微创组	21	1	1	2	4
对照组	21	4	3	4	2
χ²值		0.908	0.276	0.194	0.194
P值		0.341	0.599	0.659	0.659

组别	例数	优	良	差
微创组	21	15(71.43)	6(28.57)	0(0.00)
对照组	21	9(42.86)	6(28.57)	6(28.57)
χ²值	4.861
P值	0.027

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