| ［1］ |
王少明，郑荣寿，韩冰峰，等. 2022年中国人群恶性肿瘤发病与死亡年龄特征分析 ［J］. 中国肿瘤，2024，33（3）：165-174.
|
| ［2］ |
Clarke M，Collins R，Darby S，et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival：an overview of the randomised trials ［J］. Lancet，2005，366（9503）：2087-2106.
|
| ［3］ |
张俊萍，董新寨，李铮，等. 乳腺癌病人放射性皮炎预防性护理的研究进展 ［J］. 护理研究，2024，38（6）：1043-1046.
|
| ［4］ |
Bray FN，Simmons BJ，Wolfson AH，et al. Acute and chronic cutaneous reactions to ionizing radiation therapy ［J］. Dermatol Ther （Heidelb），2016，6（2）：185-206.
|
| ［5］ |
Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses ［J］. Eur J Epidemiol，2010，25（9）：603-605.
|
| ［6］ |
谭智琼. 利妥昔单抗联合糖皮质激素治疗原发免疫性血小板减少症的疗效及安全性meta分析［D］. 广州：暨南大学，2016.
|
| ［7］ |
郑泽源，谢芬，熊星环，等. 颈部创伤急性期致死性伤因meta分析 ［J］. 中国医药导报，2021，18（26）：115-120.
|
| ［8］ |
Abdeltawab AA，Ali SA，Mostafa HG，et al. Predictive factors increasing the risk of radiation toxicity in patients with early breast cancer ［J］. Asian Pac J Cancer Prev，2021，22（1）：145-149.
|
| ［9］ |
Córdoba EE，Lacunza E，Güerci AM. Clinical factors affecting the determination of radiotherapy-induced skin toxicity in breast cancer ［J］. Radiat Oncol J，2021，39（4）：315-323.
|
| ［10］ |
Dzul S，Ninia J，Jang H，et al. Predictors of acute radiation dermatitis and esophagitis in African American patients receiving whole-breast radiation therapy ［J］. Pract Radiat Oncol，2022，12（1）：52-59.
|
| ［11］ |
Behroozian T，Milton L，Li N，et al. Predictive factors associated with radiation dermatitis in breast cancer ［J］. Cancer Treat Res Commun，2021，28：100403.
|
| ［12］ |
Borm KJ，Loos M，Oechsner M，et al. Acute radiodermatitis in modern adjuvant 3D conformal radiotherapy for breast cancer—the impact of dose distribution and patient related factors ［J］. Radiat Oncol，2018，13（1）：218.
|
| ［13］ |
Liu D，Zheng Z，Zhang S，et al. Analysis of risk factors related to acute radiation dermatitis in breast cancer patients during radiotherapy ［J］. J Cancer Res Ther，2022，18（7）：1903-1909.
|
| ［14］ |
Xie Y，Hu T，Chen R，et al. Predicting acute radiation dermatitis in breast cancer：a prospective cohort study ［J］. BMC Cancer，2023，23（1）：537.
|
| ［15］ |
耿文慧，周严红，卢霄蒙，等. 乳腺癌术后放疗患者放射区皮肤温度与放射性皮炎程度的相关性分析 ［J］. 现代中西医结合杂志，2023，32（2）：257-260.
|
| ［16］ |
Pasquier D，Bataille B，Le Tinier F，et al. Correlation between toxicity and dosimetric parameters for adjuvant intensity modulated radiation therapy of breast cancer：a prospective study ［J］. Sci Rep，2021，11（1）：3626.
|
| ［17］ |
Chen CH，Hsieh CC，Chang CS，et al. A retrospective analysis of dose distribution and toxicity in patients with left breast cancer treated with adjuvant intensity-modulated radiotherapy：comparison with three-dimensional conformal radiotherapy ［J］. Cancer Manag Res，2020，12：9173-9182.
|
| ［18］ |
Pasquier D，Le Tinier F，Bennadji R，et al. Intensity-modulated radiation therapy with simultaneous integrated boost for locally advanced breast cancer：a prospective study on toxicity and quality of life ［J］. Sci Rep，2019，9（1）：2759.
|
| ［19］ |
Butler-Xu YS，Marietta M，Zahra A，et al. The effect of breast volume on toxicity using hypofractionated regimens for early stage breast cancer for patients ［J］. Adv Radiat Oncol，2019，4（2）：261-267.
|
| ［20］ |
Zygogianni A，Gogalis J，Georgakopoulos I，et al. Two hypofractionated schedules for early stage breast cancer：comparative retrospective analysis for acute and late radiation induced dermatitis ［J］. J BUON，2020，25（3）：1315-1322.
|
| ［21］ |
Palumbo I，Mariucci C，Falcinelli L，et al. Hypofractionated whole breast radiotherapy with or without hypofractionated boost in early stage breast cancer patients：a mono-institutional analysis of skin and subcutaneous toxicity ［J］. Breast Cancer，2019，26（3）：290-304.
|
| ［22］ |
Lin JC，Tsai JT，Chou YC，et al. Compared with intensity-modulated radiotherapy，image-guided radiotherapy reduces severity of acute radiation-induced skin toxicity during radiotherapy in patients with breast cancer ［J］. Cancer Med，2018，7（8）：3622-3629.
|
| ［23］ |
Guttmann DM，Gabriel P，Kennedy C，et al. Comparison of acute toxicities between contemporary forward-planned 3D conformal radiotherapy and inverse-planned intensity-modulated radiotherapy for whole breast radiation ［J］. Breast J，2018，24（2）：128-132.
|
| ［24］ |
De Felice F，Ranalli T，Musio D，et al. Relation between hypofractionated radiotherapy，toxicity and outcome in early breast cancer ［J］. Breast J，2017，23（5）：563-568.
|
| ［25］ |
Córdoba EE，Abba MC，Lacunza E，et al. Polymorphic variants in oxidative stress genes and acute toxicity in breast cancer patients receiving radiotherapy ［J］. Cancer Res Treat，2016，48（3）：948-954.
|
| ［26］ |
Pignol JP，Vu TT，Mitera G，et al. Prospective evaluation of severe skin toxicity and pain during postmastectomy radiation therapy ［J］. Int J Radiat Oncol Biol Phys，2015，91（1）：157-164.
|
| ［27］ |
Jagsi R，Griffith KA，Boike TP，et al. Differences in the acute toxic effects of breast radiotherapy by fractionation schedule：comparative analysis of physician-assessed and patient-reported outcomes in a large multicenter cohort ［J］. JAMA Oncol，2015，1（7）：918-930.
|
| ［28］ |
Wright JL，Takita C，Reis IM，et al. Racial variations in radiation-induced skin toxicity severity：data from a prospective cohort receiving postmastectomy radiation ［J］. Int J Radiat Oncol Biol Phys，2014，90（2）：335-343.
|
| ［29］ |
Park H，Choi DH，Noh JM，et al. Acute skin toxicity in Korean breast cancer patients carrying BRCA mutations ［J］. Int J Radiat Biol，2014，90（1）：90-94.
|
| ［30］ |
Ciammella P，Podgornii A，Galeandro M，et al. Toxicity and cosmetic outcome of hypofractionated whole-breast radiotherapy：predictive clinical and dosimetric factors ［J］. Radiat Oncol，2014，9：97.
|
| ［31］ |
Tortorelli G，Di Murro L，Barbarino R，et al. Standard or hypofractionated radiotherapy in the postoperative treatment of breast cancer：a retrospective analysis of acute skin toxicity and dose inhomogeneities ［J］. BMC Cancer，2013，13：230.
|
| ［32］ |
Terrazzino S，La Mattina P，Masini L，et al. Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery ［J］. Radiother Oncol，2012，103（2）：199-205.
|
| ［33］ |
Morganti AG，Cilla S，Valentini V，et al. Phase Ⅰ-Ⅱ studies on accelerated IMRT in breast carcinoma：technical comparison and acute toxicity in 332 patients ［J］. Radiother Oncol，2009，90（1）：86-92.
|
| ［34］ |
Freedman GM，Li T，Nicolaou N，et al. Breast intensity-modulated radiation therapy reduces time spent with acute dermatitis for women of all breast sizes during radiation ［J］. Int J Radiat Oncol Biol Phys，2009，74（3）：689-694.
|
| ［35］ |
Back M，Guerrieri M，Wratten C，et al. Impact of radiation therapy on acute toxicity in breast conservation therapy for early breast cancer ［J］. Clin Oncol （R Coll Radiol），2004，16（1）：12-16.
|
| ［36］ |
Fernando IN，Ford HT，Powles TJ，et al. Factors affecting acute skin toxicity in patients having breast irradiation after conservative surgery：a prospective study of treatment practice at the Royal Marsden Hospital ［J］. Clin Oncol （R Coll Radiol），1996，8（4）：226-233.
|
| ［37］ |
Ambrosone CB，Tian C，Ahn J，et al. Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer：a case-series study ［J］. Breast Cancer Res，2006，8（4）：R40.
|
| ［38］ |
Wright JL，Takita C，Reis IM，et al. Prospective evaluation of radiation-induced skin toxicity in a race/ethnically diverse breast cancer population ［J］. Cancer Med，2016，5（3）：454-464.
|
| ［39］ |
张顺康，陈刚. 乳腺癌改良根治术后放疗胸壁放射性皮炎的危险因素分析 ［J］. 上海交通大学学报（医学版），2015，35（7）：1034-1039.
|
| ［40］ |
Patel AK，Ling DC，Richman AH，et al. Hypofractionated whole-breast irradiation in large-breasted women-is there a dosimetric predictor for acute skin toxicities ［J］. Int J Radiat Oncol Biol Phys，2019，103（1）：71-77.
|
| ［41］ |
查耀蕾，杨凤明，金美四，等. 乳腺癌病人放疗期间症状管理体验的质性研究 ［J］. 全科护理，2023，21（34）：4885-4888.
|
| ［42］ |
Lee TF，Chang CH，Chi CH，et al. Utilizing radiomics and dosiomics with AI for precision prediction of radiation dermatitis in breast cancer patients ［J］. BMC Cancer，2024，24（1）：965.
|
| ［43］ |
Kim H，Kim J. Evaluation of the anatomical parameters for normal tissue sparing in the prone position radiotherapy with small sized left breasts ［J］. Oncotarget，2016，7（44）：72211-72218.
|
| ［44］ |
Bruand M，Salleron J，Guihard S，et al. Acute skin toxicity of conventional fractionated versus hypofractionated radiotherapy in breast cancer patients receiving regional node irradiation：the real-life prospective multicenter HYPOBREAST cohort ［J］. BMC Cancer，2022，22（1）：1318.
|
| ［45］ |
唐慧敏，黄灵炎，王明山，等. Ⅱ型糖尿病对乳腺癌预后的影响分析 ［J］. 肿瘤学杂志，2024，30（11）：924-931.
|
| ［46］ |
国家卫生和计划生育委员会.《“健康中国2030”规划纲要》辅导读本［M］. 北京：人民卫生出版社，2017.
|
| ［47］ |
Fernando IN，Bowden SJ，Herring K，et al. Synchronous versus sequential chemo-radiotherapy in patients with early stage breast cancer （SECRAB）：a randomised，phase Ⅲ，trial ［J］. Radiother Oncol，2020，142：52-61.
|
| ［48］ |
Li F，Hu W，Li H，et al. Bolus use in postmastectomy radiation therapy for breast cancer：a systematic literature review ［J］. Technol Cancer Res Treat，2025，24：15330338251344521.
|