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中华乳腺病杂志(电子版) ›› 2023, Vol. 17 ›› Issue (05) : 305 -308. doi: 10.3877/cma.j.issn.1674-0807.2023.05.009

综述

乳腺癌组织微生物群特征研究进展
吴雪烁, 冯景, 周毅()   
  1. 150001 哈尔滨医科大学附属第一医院乳腺外科
  • 收稿日期:2021-09-19 出版日期:2023-10-01
  • 通信作者: 周毅

Microbiome characteristics of breast cancer tissue

Xueshuo Wu, Jing Feng, Yi Zhou()   

  • Received:2021-09-19 Published:2023-10-01
  • Corresponding author: Yi Zhou
引用本文:

吴雪烁, 冯景, 周毅. 乳腺癌组织微生物群特征研究进展[J]. 中华乳腺病杂志(电子版), 2023, 17(05): 305-308.

Xueshuo Wu, Jing Feng, Yi Zhou. Microbiome characteristics of breast cancer tissue[J]. Chinese Journal of Breast Disease(Electronic Edition), 2023, 17(05): 305-308.

研究发现乳腺组织中也存在特殊的微生物群,其组成与丰度可能随着乳腺疾病类型和病情进展情况而发生特异性变化。乳腺癌患者微生物群失调作为一个新的风险因素与乳腺癌发展过程密切相关,并且显示出作为预后和预测性生物标志物的巨大潜力。随着微生物研究逐渐深入到单菌功能分析层面,局部组织微生物群在微环境中的组成和代谢变化在肿瘤发生、发展过程中扮演重要角色。本文旨在总结近年研究成果,描述乳房组织定植的独特微生物群,比较乳腺癌组织、正常乳房组织以及非癌性良性病变的微生物群差异,分析这种生态失调在乳腺癌发病过程中的作用,以及对微环境免疫功能和代谢变化的影响。

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