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中华乳腺病杂志(电子版) ›› 2017, Vol. 11 ›› Issue (01) : 39 -42. doi: 10.3877/cma.j.issn.1674-0807.2017.01.008

综述

循环肿瘤DNA 在乳腺癌诊疗中的应用
胡家树1, 武宸仰1, 房林1,()   
  1. 1.200072 上海市同济大学附属第十人民医院甲状腺乳腺外科
  • 收稿日期:2016-04-06 出版日期:2017-02-01
  • 通信作者: 房林

Circulating tumor DNA for diagnosis and treatment of breast cancer

Jiashu Hu, Chenyang Wu, Lin Fang()   

  • Received:2016-04-06 Published:2017-02-01
  • Corresponding author: Lin Fang
引用本文:

胡家树, 武宸仰, 房林. 循环肿瘤DNA 在乳腺癌诊疗中的应用[J/OL]. 中华乳腺病杂志(电子版), 2017, 11(01): 39-42.

Jiashu Hu, Chenyang Wu, Lin Fang. Circulating tumor DNA for diagnosis and treatment of breast cancer[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2017, 11(01): 39-42.

乳腺癌在中国的发病率和病死率呈现上升趋势,延长乳腺癌患者生存期,提高患者的生存质量面临着挑战。 循环肿瘤DNA(ctDNA)存在于癌症患者的血液循环中,便于获得,可以通过扩增子测序、肿瘤个性化分析深度测序、数码测序等技术对患者的ctDNA 进行基因分析。 ctDNA 分析结果对乳腺癌的早期诊断、药物监测及个体化治疗方案制定等方面都有一定帮助,是值得深入研究的肿瘤治疗新方向。

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