切换至 "中华医学电子期刊资源库"

中华乳腺病杂志(电子版) ›› 2016, Vol. 10 ›› Issue (05) : 264 -268. doi: 10.3877/cma.j.issn.1674-0807.2016.05.003

专家论坛

2016 年美国临床肿瘤学会年会报道:三阴性乳腺癌研究新进展
袁芃1   
  1. 1.Yuan Peng
  • 收稿日期:2016-06-16 出版日期:2016-10-01

Updates of triple-negative breast cancer from 2016 American Society of Clinical Oncology

  • Received:2016-06-16 Published:2016-10-01
引用本文:

袁芃. 2016 年美国临床肿瘤学会年会报道:三阴性乳腺癌研究新进展[J/OL]. 中华乳腺病杂志(电子版), 2016, 10(05): 264-268.

第52 届ASCO 年会在美国芝加哥盛大召开。 本届会议报告了有关三阴性乳腺癌诊疗的重要研究发现和临床试验成果。 笔者从流行病学、关键性研究、新药研究等不同方面,对本次年会中三阴性乳腺癌研究的最新进展进行综合报道。

The 52th American Society of Clinical Oncology (ASCO) annual meeting had been held in Chicago,USA. Throughout the meeting, highlights on researches and clinical updates of triple-negative breast cancer (TNBC) had been reported. This paper provided the advancement in epidemiology, practice-changing clinical trials and new drug researches on TNBC in 2016 ASCO annual meeting.

[1]
Rhiem K, Engel C,Engel J, et al. BRCA1/2 mutation prevalence in triple-negative breast cancer patients without family history of breast and ovarian cancer [J/OL]. J Clin Oncol, 2016, 34(15 suppl):1090[2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15_suppl/1090? sid=0a5136c3-2664-4077-b579-a62056883315.
[2]
Vidula N, Yau C, Wolf DM, et al. Androgen receptor (AR)expression in primary breast cancer (BC): Correlations with clinical characteristics and outcomes [J/OL]. J Clin Oncol, 2016, 34(15 suppl): 1072 [2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15_suppl/1072? sid = 934241ec-6fbc-4624-86fd-58429d5df961.
[3]
Shao ZM, Li JJ, Pang D, et al. Cbcsg-10: Adjuvant capecitabine in combination with docetaxel and cyclophosphamide plus epirubicin for triple negative breast cancer [J/OL]. J Clin Oncol, 2016,34(15 suppl): 1012 [2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15_suppl/1012? sid = aae55a8e-fa44-41b4-b3cf-99ab8678be78.
[4]
Joensuu H, Kellokumpu-Lehtinen PL, Huovinen R, et al. Adjuvant capesitabine in combination with docetaxel (T), epirubicin (E), and cyclophosphamide (C) in the treatment of early breast cancer (BC):10-year survival results from the randomized FinXX trial [J/OL]. J Clin Oncol, 2016, 34 (15 suppl):1001 [2016-06-10]. http:/ /meeting.ascopubs. org/cgi/content/abstract/34/15_suppl/1001? sid=496b684b-2491-422d-a7e8-7646c75636d2.
[5]
Joensuu H, Kellokumpu-Lehtinen PL,Huovinen R,et al. Adjuvant capecitabine, docetaxel, cyclophosphamide, and epirubicin for early breast cancer: final analysis of the randomized FinXX trial [J]. J Clin Oncol,2012,30(1):11-18.
[6]
Yuan P, Du F, Wang JY, et al. Comparison of four cycles epirubicin and cyclophosphamide (EC) followed by four cycles docetaxel (T)versus six cycles docetaxel and carboplatin ( TP) as adjuvant chemotherapy for women with operable triple negative breast cancer [J/OL].J Clin Oncol,2016,34(15 suppl):1068[2016-06-10]. http:/ /meeting.ascopubs. org/cgi/content/abstract/34/15_suppl/1068? sid=31ab5b91-8746-411d-ba61-a6e5c55d49af.
[7]
Takahashi M,Yonemori K,Yamamoto H,et al. A phase Ⅰ/Ⅱtrial of olaparib in combination with eribulin in patients with advanced or metastatic triple negative breast cancer (TNBC) previously treated with anthracyclines and taxanes: The analyses of efficacy and safety from phase Ⅱ[J/OL].J Clin Oncol,2016,34(15 suppl): 1080[2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15 _suppl/1080? sid=67582b01-a5de-45a7-9c81-31bb1e6f02a7.
[8]
Brufsky A, Kim SB, Velu TJ, et al. Cobimetinib (C)+paclitaxel (P)as first-line treatment in patients (pts) with advanced triple-negative breast cancer (TNBC): Updated results and biomarker data from the phase 2 COLET study [J/OL].J Clin Oncol,2016,34(15 suppl):1074[2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15_suppl/1074? sid=e53e0f0c-bee2-4446-85c5-4b92f1b09916.
[9]
Adams S, Diamond JR, Hamilton EP, et al. Phase Ib trial of atezolizumab in combination with nab-paclitaxel in patients with metastatic triple-negative breast cancer (mTNBC) [J/OL]. J Clin Oncol,2016, 34(15 suppl):1009[2016-06-10]. http:/ /meeting.ascopubs. org/cgi/content/abstract/34/15 _ suppl/1009? sid =ea0f16d5-e998-4447-9e14-5a1b141dc71c.
[10]
Becerra C, Braiteh FS,Spira AI,et al. A phase Ib/Ⅱstudy of cancer stemness inhibitor napabucasin (BB608) combined with weekly paclitaxel in advanced triple negative breast cancer [J/OL]. J Clin Oncol,2016,34(15 suppl): 1094[2016-06-10]. http:/ /meeting.ascopubs. org/cgi/content/abstract/34/15 _ suppl/1094? sid =944337ed-8c30-4af5-9bbf-6336622eda04.
[11]
Tung NM, Garber JE, Hacker MR, et al. Distant recurrences in triple negative breast cancer (TNBC) according to androgen receptor (AR)status [J/OL]. J Clin Oncol,2016,34(15 suppl): 1085[2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15 _suppl/1085? sid=77904a3d-ac56-497a-ab77-c629fdf3e877.
[12]
Bhattarai S, Xia J, Wetherilt CS, et al. A multi-institutional study of racial differences in androgen receptor status among triple-negative breast cancers [J/OL]. J Clin Oncol,2016,34(15 suppl): 1089[2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15_suppl/1089? sid=3389a8e9-0ab6-47ed-8fde-190ae9d38b2d.
[13]
Afghahi A, Rigdon J, Purington N, et al. Higher peripheral lymphocyte count to predict survival in triple-negative breast cancer(TNBC) [J/OL].J Clin Oncol,2016,34(15 suppl): 1010[2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15 _suppl/1010? sid=4ba93683-b32b-4e2f-8d59-39a0b2f13b7b.
[14]
Klimov S, Green AR, Aleskandarany M, et al. Identifying likely metastatic sites for triple negative breast cancers using immunohistochemical biomarkers [J/OL]. J Clin Oncol,2016,34(15 suppl): 1092 [2016-06-10]. http:/ /meeting. ascopubs. org/cgi/content/abstract/34/15_suppl/1092? sid= e5869ccc-0cfa-4c74-b90eb6129d61baeb.
[1] 史学兵, 谢迎东, 谢霓, 徐超丽, 杨斌, 孙帼. 声辐射力弹性成像对不可切除肝细胞癌门静脉癌栓患者放射治疗效果的评价[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 778-784.
[2] 曹琮沅, 黄烁金, 何倩婷, 王安训. 平阳霉素复合剂治疗口腔颌面部脉管畸形的有效性和安全性[J/OL]. 中华口腔医学研究杂志(电子版), 2024, 18(06): 368-374.
[3] 严华悦, 刘子祥, 周少波. 磷酸烯醇式丙酮酸羧激酶-1在恶性肿瘤中的研究进展[J/OL]. 中华普通外科学文献(电子版), 2024, 18(06): 452-456.
[4] 高俊颖, 张海洲, 区泓乐, 孙强. FOLFOX-HAIC 为基础的肝细胞癌辅助转化治疗的应用进展[J/OL]. 中华普通外科学文献(电子版), 2024, 18(06): 457-463.
[5] 李华志, 曹广, 刘殿刚, 张雅静. 不同入路下行肝切除术治疗原发性肝细胞癌的临床对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 52-55.
[6] 高杰红, 黎平平, 齐婧, 代引海. ETFA和CD34在乳腺癌中的表达及与临床病理参数和预后的关系研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 64-67.
[7] 陈浩, 王萌. 胃印戒细胞癌的临床病理特征及治疗选择的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 108-111.
[8] 韩萌萌, 冯雪园, 马宁. 乳腺癌改良根治术后桡神经损伤1例[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 117-118.
[9] 刘柏隆, 周祥福. 压力性尿失禁阶梯治疗的项目介绍[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 125-125.
[10] 刘柏隆. 女性压力性尿失禁阶梯治疗之手术治疗方案选择[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 126-126.
[11] 袁园园, 岳乐淇, 张华兴, 武艳, 李全海. 间充质干细胞在呼吸系统疾病模型中肺组织分布及治疗机制的研究进展[J/OL]. 中华细胞与干细胞杂志(电子版), 2024, 14(06): 374-381.
[12] 陈杰, 武明胜, 李一金, 李虎, 向源楚, 荣新奇, 彭健. 低位直肠癌冷冻治疗临床初步分析[J/OL]. 中华结直肠疾病电子杂志, 2024, 13(06): 494-498.
[13] 国文凯, 纪鹏程, 毕靖茹, 谢院生. IgA 肾病的十种治疗措施[J/OL]. 中华肾病研究电子杂志, 2024, 13(06): 327-333.
[14] 王誉英, 刘世伟, 王睿, 曾娅玲, 涂禧慧, 张蒲蓉. 老年乳腺癌新辅助治疗病理完全缓解的预测因素分析[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 641-646.
[15] 崔军威, 蔡华丽, 胡艺冰, 胡慧. 亚甲蓝联合金属定位夹及定位钩针标记在乳腺癌辅助化疗后评估腋窝转移淋巴结的临床应用价值探究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 625-632.
阅读次数
全文


摘要