目的

比较隐匿性乳腺癌与非隐匿性乳腺癌患者的临床特征。

方法

回顾性分析天津肿瘤医院1981年1月至2000年12月期间收治的96例隐匿性乳腺癌患者的临床病例资料，随机抽取同期入院的女性可手术非隐匿性乳腺癌病例并进行比较。

结果

隐匿性乳腺癌与非隐匿性乳腺癌患者的ER阳性率分别为42.1%和57.3%，PR阳性率为44.3%和55.9%。隐匿性乳腺癌和非隐匿性乳腺癌不同时期的复发和／或转移率分别为25.6%～66.7%和13.5%～28.2%。隐匿性乳腺癌患者5年、10年总生存率分别为55%和46%；0～Ⅰ期、Ⅱ期及Ⅲ期非隐匿性乳腺癌患者的5年总生存率分别为94%、86%、56%，10年总生存率分别为86%、78%、和47%。

结论

与非隐匿性乳腺癌相比较，隐匿性乳腺癌ER、PR阳性率低，复发和／或转移率高，5、10年总生存率与Ⅲ期乳腺癌患者相仿。

Objective

To compare the clinical features of occult breast cancer and non-occult breast cancer.

Methods

Clinical data of 96 patients with occult breast cancer treated in Tianjin Cancer Hospital from Jan 1981 to Dec 2000 were retrospectively analyzed and compared with the data of non-occult breast cancer patients who were sampled randomly in the same period.

Results

The ER-positive rates of occult breast cancer and non-occult breast cancer were 42.1% and 57.3%，respectively.The PR-positive rates of occult breast cancer and non-occult breast cancer were 44.3% and 55.9%，respectively.The recurrence and／or distant metastasis rates of occult breast cancer and non-occult breast cancer in different periods were 25.6%-66.7% and 13.5%-28.2%，respectively.The overall 5-and 10-year survival rates of the 96 patients were 55% and 46%，respectively.The overall 5-year survival rates of stage 0-Ⅰ，ⅡandⅢof non-occult breast cancer patients were 94%，86% and 56%，respectively，and the overall 10-year survival rates were 86%，78%and 47%，respectively.

Conclusion

Compared with non-occult breast cancer patients，the patients of occult breast cancer have low ER／PR-positive rates，high recurrence and／or distant metastasis rates.The overall 5-and 10-year survival rates of occult breast cancer patients are similar to those of stageⅢnon-occult breast cancer.