Abstract:

Objective

To explore the related factors in the development from acute lactation mastitis to breast abscess.

Methods

The clinical data of 111 patients who had lactation mastitis or breast abscess in our department from January 2013 to March 2014, including 92 cases of lactation mastitis and 19 cases of breast abscess, were analyzed retrospectively. Single factor analysis and unconditional logistic regression analysis were used from the following aspects: fever or not, duration of fever, infection site, massage history given by nonmedical staff, use of antibiotics,switching to sensitive antibiotics or not,bacterial culture of breast milk,mass,age, and routine blood test.

Results

Single factor analysis showed that in breast abscess group, the proportion of the patients with duration of fever ＞2 d, lesions in nipple-areola area and massage history given by nonmedical staff were 12/19,9/19 and 5/19, significantly higher than 27.2% (25/92), 15.2% (14/92) and 4.3% (4/92) in non-abscess group (χ²=9.176,9.909,7.465, P=0.002,0.002,0.006). Multiple factor logistic regression analysis showed that duration of fever ＞2 d, lesions in nipple-areola area and massage history given by non-medical staff were risk factors in breast abscess during lactation (OR=4.171, 95%CI: 1.325-13.135,P=0.015; OR=5.153,95%CI: 1.564-16.972,P=0.007;OR=10.184, 95%CI: 2.017-51.428,P=0.005).

Conclusion

The patients with duration of fever ＞2 d, lesions in nipple-areola area and massage history given by non-medical staff are prone to develop breast abscess and the physicians should pay more attention to their treatment.

Key words: Acute disease, Mastitis, Abscess, Retrospective studies, Time factor