切换至 "中华医学电子期刊资源库"

中华乳腺病杂志(电子版) ›› 2019, Vol. 13 ›› Issue (02) : 118 -120. doi: 10.3877/cma.j.issn.1674-0807.2019.02.011

所属专题: 文献

综述

前哨淋巴结微转移与腋窝淋巴结复发关系的研究进展
解新鹏1, 刘维芳1, 张宇1, 吴迪1, 张秀祥1, 徐格格1, 杨霞1, 石爱平1,()   
  1. 1. 130021 长春,吉林大学白求恩第一医院乳腺外科
  • 收稿日期:2018-07-19 出版日期:2019-04-01
  • 通信作者: 石爱平

Relationship between sentinel lymph node micrometastasis and axillary lymph node recurrence

Xinpeng Xie1, Weifang Liu1, Yu Zhang1   

  • Received:2018-07-19 Published:2019-04-01
引用本文:

解新鹏, 刘维芳, 张宇, 吴迪, 张秀祥, 徐格格, 杨霞, 石爱平. 前哨淋巴结微转移与腋窝淋巴结复发关系的研究进展[J/OL]. 中华乳腺病杂志(电子版), 2019, 13(02): 118-120.

Xinpeng Xie, Weifang Liu, Yu Zhang. Relationship between sentinel lymph node micrometastasis and axillary lymph node recurrence[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2019, 13(02): 118-120.

乳腺癌是女性最常见的恶性肿瘤,而腋窝淋巴结的转移状态与乳腺癌患者的预后相关。自从开展乳腺癌前哨淋巴结活组织检查以来,一部分乳腺癌患者因前哨淋巴结阴性而免除了腋窝淋巴结清扫,而另一部分患者因前哨淋巴结微转移选择术后放射治疗或是化疗以替代腋窝淋巴结清扫,从而减少了患侧上肢淋巴水肿、运动障碍以及感觉障碍等并发症的发生。近年来,少部分前哨淋巴结微转移患者发生了不同程度的腋窝淋巴结复发。对此,部分学者认为前哨淋巴结微转移患者即使不做腋窝淋巴结清扫,腋窝淋巴结复发率也未见明显增加;但部分学者则认为前哨淋巴结微转移应被视为腋窝淋巴结转移,残留的肿瘤病灶能增加腋窝淋巴结复发率,因此应行腋窝淋巴结清扫术。对于前哨淋巴结微转移的处理方式,国内外专家尚未得出一致的结论。目前众多研究者仍在不懈地进行相关临床试验及大数据分析,旨在为前哨淋巴结微转移患者寻求更佳的治疗方案。

[1]
Halsted WS. The results of operations for the cure of cancer of the breast performed at the Johns Hopkins Hospital from June, 1889, to January, 1894[J]. Ann Surg, 1894, 20(5):497-555.
[2]
Giuliano AE, Ballman K, McCall L, et al. Locoregional recurrence after sentinel lymph node dissection with or without axillary dissection in patients with sentinel lymph node metastases: long-term follow-up from the American College of Surgeons Oncology Group (Alliance) ACOSOG Z0011 randomized trial [J].Ann Surg, 2016, 264(3):413-420.
[3]
Vijayaraghavan GR, Vedantham S, Kataoka M, et al. The relevance of ultrasound imaging of suspicious axillary lymph nodes and fine-needle aspiration biopsy in the post-ACOSOG Z11 era in early breast cancer[J].Acad Radiol, 2017, 24 (3):308-315.
[4]
Giuliano AE, Ballman KV, McCall L, et al. Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis: the ACOSOG Z0011 (Alliance) randomized clinical trial [J].JAMA, 2017, 318(10):918-926.
[5]
Wetzig N, Gill PG, Espinoza D, et al. Sentinel-lymph-node-based management or routine axillary clearance five-year outcomes of the RACS sentinel node biopsy versus axillary clearance (SNAC) 1 trial: assessment and incidence of true lymphedema[J].Ann Surg Oncol, 2017, 24(4):1064-1070.
[6]
张晓东,梁运升.乳腺癌前哨淋巴结检测及其临床意义[J].解放军预防医学杂志,2018, 36(4):477-479.
[7]
Ibis K, Ozkurt S, Kucucuk S, et al. Comparison of pathological prognostic stage and anatomic stage groups according to the updated version of the American Joint Committee on Cancer (AJCC) breast cancer staging 8th edition [J].Med Sci Monit, 2018, 24:3637-3643.
[8]
Tallet A, Lambaudie E, Cohen M, et al. Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy [J]. World J Clin Oncol, 2016, 7(2): 243-252.
[9]
Jagsi R, Chadha M, Moni J, et al. Radiation field design in the ACOSOG Z0011 (Alliance) trial[J]. J Clin Oncol, 2014, 32(32):3600-3606.
[10]
Pepels MJ, de Boer M, Bult P, et al. Regional recurrence in breast cancer patients with sentinel node micrometastases and isolated tumor cells [J].Ann Surg, 2012, 255(1):116-121.
[11]
Francissen CM, Dings PJ, van Dalen T, et al. Axillary recurrence after a tumor-positive sentinel lymph node biopsy without axillary treatment: a review of the literature [J]. Ann Surg Oncol, 2012, 19(13):4140-4149.
[12]
de Boer M, van Deurzen CH, van Dijck JA, et al. Micrometastases or isolated tumor cells and the outcome of breast cancer [J]. N Engl J Med, 2009, 36(1): 653-663.
[13]
Galimberti V, Cole BF, Zurrida S, et al. Axillary dissection versus no axillary dissection in patients with sentinel node micrometastases (IBCSG 23-01): a phase 3 randomized controlled trial[J]. Lancet Oncol, 2013, 14(4): 297-305.
[14]
Veronesi U, Paganelli G, Viale G, et al. A randomized comparison of sentinel node biopsy with routine axillary dissection in breast cancer[J].N Engl J Med, 2003, 349(6):546-553.
[15]
Giuliano AE, McCall L, Beitsch P, et al. Locoregional recurrence after sentinel lymph node dissection with or without axillary dissection in patients with sentinel lymph node metastases: the American College of Surgeons Oncology Group Z0011 randomized trial[J].Ann Surg, 2010, 252(3):426-432.
[16]
Belmonte R, Messaggi-Sartor M, Ferrer M, et al. Prospective study of shoulder strength, shoulder range of motion, and lymphedema in breast cancer patients from pre-surgery to 5 years after ALND or SLNB [J].Support Care Cancer, 2018, 26 (9): 3277-3287.
[17]
Siotos C, Sebai ME, Wan EL, et al. Breast reconstruction and risk of arm lymphedema development: A meta analysis[J].J Plast Reconstr Aesthet Surg, 2018, 71(6):807-818.
[18]
Gratzon A, Schultz J, Secrest K, et al.Clinical and psychosocial outcomes of vascularized lymph node transfer for the treatment of upper extremity lymphedema after breast cancer therapy[J].Ann Surg Oncol, 2017, 24(6):1475-1481.
[19]
Krag DN, Anderson SJ, Julian TB, et al. Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial [J].Lancet Oncol, 2010, 11(10):927-933.
[20]
Van Zee KJ, Kattan MW. Validating a predictive model for presence of additional disease in the non-sentinel lymph nodes of a woman with sentinel node positive breast cancer [J].Ann Surg Oncol, 2007, 14(8):2177-2178.
[21]
Malter W, Hellmich M, Badian M, et al. Factors predictive of sentinel lymph node involvement in primary breast cancer [J].Anticancer Res, 2018, 38(6):3657-3662.
[22]
Nowikiewicz T, Zegarski W, Pagacz K, et al. The current application of ACOSOG Z0011 trial results: Is further implementation of sentinel lymph node intra-operative histopathological examination mandatory in breast cancer patients-a single-centre analysis [J].Neoplasma, 2018, 65(3):449-454.
[23]
Geertsema D, Gobardhan PD, Madsen EV, et al. Discordance of intraoperative frozen section analysis with definitive histology of sentinel lymph nodes in breast cancer surgery: complementary axillary lymph node dissection is irrelevant for subsequent systemic therapy[J].Ann Surg Oncol, 2010, 17(10):2690-2695.
[24]
Jakub JW, Bryant K, Huebner M, et al. The number of axillary lymph nodes involved with metastatic breast cancer does not affect outcome as long as all disease is confined to the sentinel lymph nodes[J].Ann Surg Oncol, 2011, 18(1):86-93.
[1] 王佳佳, 詹韵韵, 姜凡, 孙碧云, 毕玉, 李如冰, 彭梅. Peyton四步教学法在超声住院医师规范化培训颈部淋巴结分区中的应用[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 814-818.
[2] 李洋, 蔡金玉, 党晓智, 常婉英, 巨艳, 高毅, 宋宏萍. 基于深度学习的乳腺超声应变弹性图像生成模型的应用研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(06): 563-570.
[3] 河北省抗癌协会乳腺癌专业委员会护理协作组. 乳腺癌中心静脉通路护理管理专家共识[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 321-329.
[4] 李乐平, 张荣华, 商亮. 腹腔镜食管胃结合部腺癌根治淋巴结清扫策略[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 9-12.
[5] 吴晖, 佴永军, 施雪松, 魏晓为. 两种解剖入路下行直肠癌侧方淋巴结清扫的效果比较[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 40-43.
[6] 周世振, 朱兴亚, 袁庆港, 刘理想, 王凯, 缪骥, 丁超, 汪灏, 管文贤. 吲哚菁绿荧光成像技术在腹腔镜直肠癌侧方淋巴结清扫中的应用效果分析[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 44-47.
[7] 高杰红, 黎平平, 齐婧, 代引海. ETFA和CD34在乳腺癌中的表达及与临床病理参数和预后的关系研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 64-67.
[8] 韩萌萌, 冯雪园, 马宁. 乳腺癌改良根治术后桡神经损伤1例[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 117-118.
[9] 林逸, 钟文龙, 李锴文, 何旺, 林天歆. 广东省医学会泌尿外科疑难病例多学科会诊(第15期)——转移性膀胱癌的综合治疗[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(06): 648-652.
[10] 刘敏思, 李荣, 李媚. 基于GGT与Plt比值的模型在HBV相关肝细胞癌诊断中的作用[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(06): 831-835.
[11] 陆镜明, 韩大为, 任耀星, 黄天笑, 向俊西, 张谞丰, 吕毅, 王傅民. 基于术前影像组学的肝内胆管细胞癌淋巴结转移预测的系统性分析[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(06): 852-858.
[12] 张润锦, 阳盼, 林燕斯, 刘尊龙, 刘建平, 金小岩. EB病毒相关胆管癌伴多发转移一例及国内文献复习[J/OL]. 中华肝脏外科手术学电子杂志, 2024, 13(06): 865-869.
[13] 刘郁, 段绍斌, 丁志翔, 史志涛. miR-34a-5p 在结肠癌患者的表达及其与临床特征及预后的相关性研究[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(06): 485-490.
[14] 崔军威, 蔡华丽, 胡艺冰, 胡慧. 亚甲蓝联合金属定位夹及定位钩针标记在乳腺癌辅助化疗后评估腋窝转移淋巴结的临床应用价值探究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 625-632.
[15] 王曦娅, 尹弘青, 丁伟, 徐滨, 于海源, 马东升, 邵军. 桥本背景下甲状腺乳头状癌多参数分析预测大容量淋巴结转移[J/OL]. 中华临床医师杂志(电子版), 2024, 18(06): 548-554.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?