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中华乳腺病杂志(电子版) ›› 2025, Vol. 19 ›› Issue (01) : 39 -44. doi: 10.3877/cma.j.issn.1674-0807.2025.01.007

综述

囊性中性粒细胞性肉芽肿性乳腺炎发病机制及诊疗进展
王梦洁1, 张董晓2,()   
  1. 1.100010 北京,首都医科大学附属北京中医医院乳腺科
    2.100029 北京,北京中医药大学临床医学院/北京中医医院乳腺科
  • 收稿日期:2024-06-11 出版日期:2025-02-01
  • 通信作者: 张董晓
  • 基金资助:
    青年岐黄学者项目(2022 年)国家中医药管理局中医药古籍文献和特色技术传承专项(GZY-KJS-2022-035)北京中医药大学研究生自主科研课题(ZJKT2023119)

Pathogenesis, diagnosis and treatment of cystic neutrophilic granulomatous mastitis

Mengjie Wang, Dongxiao Zhang()   

  • Received:2024-06-11 Published:2025-02-01
  • Corresponding author: Dongxiao Zhang
引用本文:

王梦洁, 张董晓. 囊性中性粒细胞性肉芽肿性乳腺炎发病机制及诊疗进展[J/OL]. 中华乳腺病杂志(电子版), 2025, 19(01): 39-44.

Mengjie Wang, Dongxiao Zhang. Pathogenesis, diagnosis and treatment of cystic neutrophilic granulomatous mastitis[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2025, 19(01): 39-44.

囊性中性粒细胞性肉芽肿性乳腺炎(CNGM)是一类与细菌感染相关的良性乳腺炎症性疾病,近年来因其发病率升高、临床表现复杂、病程延绵、复发率高等特点逐渐受到大家重视,但其病因及发病机制尚不明确。 该病好发于育龄期女性,以乳房局部肿块、红肿、疼痛为主要表现,部分患者后期形成脓肿,伴有破溃及窦道形成,部分患者会出现包括结节性红斑、干咳、头痛等在内的全身症状。 目前主要依据组织病理学对其进行诊断,尚无统一的治疗标准,多应用抗生素、激素、免疫抑制剂等进行药物治疗或接受手术治疗及多种方式联合治疗。 本文主要对CNGM 的发病机制、临床特征及临床诊疗最新进展进行总结。

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