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中华乳腺病杂志(电子版) ›› 2024, Vol. 18 ›› Issue (05) : 304 -307. doi: 10.3877/cma.j.issn.1674-0807.2024.05.009

综 述

乳腺导管原位癌的浸润转化机制及临床病理特征
于桐1, 孙姗姗1, 刘扬1,()   
  1. 1.150081 哈尔滨医科大学附属肿瘤医院乳腺整形科
  • 收稿日期:2023-11-13 出版日期:2024-10-01
  • 通信作者: 刘扬

Invasion mechanism and clinicopathological features of ductal carcinoma in situ

Tong Yu, Shanshan Sun, Yang Liu()   

  • Received:2023-11-13 Published:2024-10-01
  • Corresponding author: Yang Liu
引用本文:

于桐, 孙姗姗, 刘扬. 乳腺导管原位癌的浸润转化机制及临床病理特征[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(05): 304-307.

Tong Yu, Shanshan Sun, Yang Liu. Invasion mechanism and clinicopathological features of ductal carcinoma in situ[J/OL]. Chinese Journal of Breast Disease(Electronic Edition), 2024, 18(05): 304-307.

乳腺导管原位癌(DCIS) 是一种局限在乳腺导管内的非浸润性乳腺癌,被认为是浸润性导管癌(IDC) 的潜在前体。 近年来,研究发现部分DCIS 病例在未经治疗的情况下会发展成IDC。 此外,IDC 与DCIS 的共存(IDC-DCIS) 在临床上也比较常见,而这2 种病变的共存可能影响患者的临床特征及预后。 IDC 是一种已经突破乳腺导管基底膜并侵入周围组织的乳腺癌,是最常见的乳腺癌类型。与单纯IDC 相比,IDC-DCIS 患者可能在肿瘤分级、生物学特性、治疗响应和远期转移风险等方面表现出差异。 为了深入理解DCIS 如何发展为IDC,以及IDC-DCIS 患者的临床特征和预后影响,笔者对现有文献进行综述,以期更好地理解DCIS 到IDC 的进展机制,为临床治疗提供指导,并帮助预测患者的预后。

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