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中华乳腺病杂志(电子版) ›› 2021, Vol. 15 ›› Issue (04) : 259 -262. doi: 10.3877/cma.j.issn.1674-0807.2021.04.014

所属专题: 经典病例

病例报告

乳腺原发性血管肉瘤一例
甄潮辉1, 梁博1, 曾山2, 巩鹏1,()   
  1. 1. 518055 深圳大学总医院普外科
    2. 518055 深圳大学总医院病理科
  • 收稿日期:2020-03-13 出版日期:2021-09-08
  • 通信作者: 巩鹏

Primary angiosarcoma of the breast: one case report

Chaohui Zhen1, Bo Liang1, Shan Zeng2   

  • Received:2020-03-13 Published:2021-09-08
引用本文:

甄潮辉, 梁博, 曾山, 巩鹏. 乳腺原发性血管肉瘤一例[J]. 中华乳腺病杂志(电子版), 2021, 15(04): 259-262.

Chaohui Zhen, Bo Liang, Shan Zeng. Primary angiosarcoma of the breast: one case report[J]. Chinese Journal of Breast Disease(Electronic Edition), 2021, 15(04): 259-262.

图1 右侧乳腺血管肉瘤患者乳腺增强MRI图象 a图为T2WI呈不均匀高信号;b图为T1WI上呈等信号,可见不均匀短T1信号;c图为T2WI矢状位上可见斑片状及线状低信号影及明显假包膜;d、e、f图为连续动态增强扫描,肿瘤呈进行性强化
图2 右侧乳腺血管肉瘤病理表现 a图所示肿瘤细胞呈迷路样及实质细胞巢状生长(HE ×200);b图箭头所示血管内皮细胞异型性明显,可见核分裂象(HE ×400);c图所示肿瘤细胞浸润脂肪组织(HE ×200);d图所示肿瘤细胞浸润乳腺小叶组织,破坏正常小叶结构(HE ×200)
图3 右侧乳腺血管肉瘤组织免疫组织化学染色图像(SP ×200) a图为CD34免疫组织化学染色阳性;b图为Ki-67免疫组织化学染色阳性
[1]
Nascimento AF, Raut CP, Fletcher CD. Primary angiosarcoma of the breast: clinicopathologic analysis of 49 cases, suggesting that grade is not prognostic[J]. Am J Surg Pathol, 2008, 32(12): 1896-1904.
[2]
Fayette J, Martin E, Piperno-Neumann S, et al. Angiosarcomas, a heterogeneous group of sarcomas with specific behavior depending on primary site: a retrospective study of 161 cases[J]. Ann Oncol, 2007, 18(12): 2030-2036.
[3]
Adem C, Reynolds C, Ingle JN, et al. Primary breast sarcoma: Clinicopathologic series from the Mayo Clinic and review of the literature[J]. Br J Cancer, 2004, 91(2): 237-241.
[4]
Lakhani SR, Ellis LO, Schnitt SJ, et al. WHO classification of tumoures of the breast[M]. Lyon: IARC Press, 2012: 135-136.
[5]
Uryvaev A, Moskovitz M, Abdach-Bortnyak R, et al. Post-irradiation angiosarcoma of the breast: clinical presentation and outcome in a series of six cases[J]. Breast Cancer Res Treat, 2015, 153(1): 3-8.
[6]
Scow JS, Reynolds CA, Degnim AC, et al. Primary and secondary angiosarcoma of the breast: the Mayo Clinic experience[J]. J Surg Oncol, 2010, 101(5): 401-407.
[7]
Yang WT, Hennessy BT, Dryden MJ, et al. Mammary angiosarcomas: imaging findings in 24 patients[J]. Radiology, 2007, 242(3): 725-734.
[8]
O’Neill AC, D’Arcy C, McDermott E, et al. Magnetic resonance imaging appearances in primary and secondary angiosarcoma of the breast[J]. J Med Imaging Radiat Oncol, 2014, 58(2): 208-212.
[9]
Fraga-Guedes C, Gobbi H, Mastropasqua MG, et al. Primary and secondary angiosarcomas of the breast: a single institution experience[J]. Breast Cancer Res Treat, 2012, 132(3): 1081-1088.
[11]
刘红,赵晶,付丽. 乳腺原发性血管肉瘤的诊断治疗进展[J]. 中国肿瘤临床2006, 33(15): 897-899.
[12]
McKay KM, Doyle LA, Lazar AJ, et al. Expression of ERG, an Ets family transcription factor, distinguishes cutaneous angiosarcoma from histological mimics[J]. Histopathology, 2012, 61(5): 989-991.
[13]
刘高秀,李文涛,吴凯彦,等. 乳腺原发性血管肉瘤一例[J]. 郑州大学学报(医学版), 2018, 53(3): 399-400.
[14]
Yoshida A, Tsuta K, Ohno M, et al. STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors[J]. Am J Surg Pathol, 2014, 38(4): 552-559.
[15]
Alvarado-Miranda A, Bacon-Fonseca L, Ulises Lara-Medina F, et al. Thalidomide combined with neoadjuvant chemotherapy in angiosarcoma of the breast with complete pathologic response: case report and review of literature[J]. Breast Care (Basel), 2013, 8(1): 74-76.
[16]
马榕,张凯. 乳腺原发性血管肉瘤的临床病理特征及术式选择[J]. 中国实用外科杂志2013, 33(3): 244-246.
[17]
Toesca A, Spitaleri G, De Pas T, et al. Sarcoma of the breast: outcome and reconstructive options[J]. Clin Breast Cancer, 2012, 12(6): 438-444.
[18]
Scott MT, Portnow LH, Morris CG, et al. Radiation therapy for angiosarcoma: the 35-year University of Florida experience[J]. Am J Clin Oncol, 2013, 36(2): 174-180.
[19]
Torres KE, Ravi V, Kin K, et al. Long-term outcomes in patients with radiation-associated angiosarcomas of the breast following surgery and radiotherapy for breast cancer[J]. Ann Surg Oncol, 2013, 20(4): 1267-1274.
[20]
Stacchiotti S, Palassini E, Sanfilippo R, et al. Gemcitabine in advanced angiosarcoma: a retrospective case series analysis from the Italian Rare Cancer Network[J]. Ann Oncol, 2012, 23(2): 501-508.
[21]
Sher T, Hennessy BT, Valero V, et al. Primary angiosarcomas of the breast[J]. Cancer, 2007, 110(1): 173-178.
[22]
Fields RC, Aft RL, Gillanders WE, et al. Treatment and outcomes of patients with primary breast sarcoma[J]. Am J Surg, 2008, 196(4): 559-561.
[23]
Rohan VS, Hanji AM, Patel JJ, et al. Primary angiosarcoma of the breast in a postmenopausal patient[J]. J Cancer Res Ther, 2010, 6(1): 120-122.
[24]
Glazebrook KN, Magut MJ, Reynolds C. Angiosarcoma of the breast[J]. AJR Am J Roentgenol, 2008, 190(2): 533-538.
[25]
Shet T, Malaviya A, Nadkarni M, et al. Primary angiosarcoma of the breast: observations in Asian Indian women[J]. J Surg Oncol, 2006, 94(5): 368-374.
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