互联网＋临床实践是新型医疗资源管理方式和卫生服务业态。在互联网＋乳腺日间手术项目中，笔者对其理论设计及关键技术进行了系统研究。其中，理论设计包括多学科合作为基础的顶层系统设计、以问题为导向的新型工作模式设计、以患者参与为重点的人性化设计和以医疗规章制度及医学伦理原则为指导的论证设计。为了实现理论设计，形成和完善了7项关键技术，包括：统一语言环境技术、网络整合和拼接技术、病历自动生成技术、针对患者的一站式服务技术、实现患者主动参与的关键技术和网络安全及患者隐私保护技术。通过学科专项问题调研、应用定义、问题分析、服务定位、设计规划、临床体验、修改完善等线路框架的逐步推进，最终实现互联网＋乳腺日间手术临床应用。该模式省时快捷、应用方便、经济高效，患者参与度显著提高和安全性良好，具有明显的示范效应。

The Internet + clinical practice is a new model of medical resource management and healthcare service. By the practice of Internet + ambulatory breast surgery, we made a systematic research on the key technologies and theoretical design. The theoretical design includes top-level system based on multidisciplinary collaboration, new problem-oriented work mode, patient-centered individualized treatment and demonstration design guided by medical regulations and medical ethic principles. In order to achieve those theoretical goals, seven key technologies have been developed, including unified language environment technology, network integration and splicing technology, automatic generation of medical records, one-stop patient-centered service, key technologies for achieving active participation of patients, online security and patient privacy protection. Through the process of survey and research on special subjects of this discipline, definition and application, problem analysis, service orientation, design planning, clinical experience, revision and improvement, the clinical application of Internet + ambulatory breast surgery is gradually achieved. It has the advantages of being time-saving, convenient and efficient, less cost, significantly increased patient participation and high safety, thus producing remarkable demonstration effect.